Carbomer na hydroxyethylcellulose (HEC) bụ ihe ndị a na-ejikarị eme ihe na ụlọ ọrụ dị iche iche, karịsịa na ihe ịchọ mma, ọgwụ na ngwaahịa nlekọta onwe onye. N'agbanyeghị ngwa ha yiri nke ahụ dị ka ihe na-eme ka ihe na-eme ka ahụ sie ike na stabilizers, ha nwere ihe mejupụtara kemịkalụ, akụrụngwa na ngwa dị iche iche.
1. Ngwakọta kemịkalụ:
Carbomer: Carbomers bụ sịntetik dị elu molekul arọ polymers nke acrylic acid cross-njikọ na polyalkenyl ethers ma ọ bụ divinyl glycol. A na-emepụtakarị ha site na mmeghachi omume polymerization.
Hydroxyethylcellulose: Hydroxyethylcellulose, n'aka nke ọzọ, bụ ihe sitere na cellulose, polymer na-apụta n'okike. A na-emepụta ya site n'ịgwọ cellulose na sodium hydroxide na ethylene oxide iji webata otu hydroxyethyl na ọkpụkpụ azụ cellulose.
2. Ọdịdị Molecular:
Carbomer: Carbomers nwere usoro ihe omimi nke alaka n'ihi ọdịdị ha jikọtara ọnụ. Nke a branching na-enye aka na ha ike na-etolite a atọ akụkụ netwọk mgbe hydrated, na-eduga na oru oma ndim na gelling Njirimara.
Hydroxyethylcellulose: Hydroxyethylcellulose na-ejigide nhazi usoro nke cellulose, yana otu hydroxyethyl jikọtara na nkeji glucose n'akụkụ ụdọ polymer. Usoro ahịrị ahịrị a na-emetụta omume ya dị ka ihe na-eme ka ọ sie ike na nkwụsi ike.
3. Solubility:
Carbomer: A na-enyekarị carbomers n'ụdị ntụ ntụ ma bụrụ nke a na-adịghị ahụkebe na mmiri. Otú ọ dị, ha nwere ike zaa na hydrate na aqueous ngwọta, akpụ transperent gels ma ọ bụ viscous dispersions.
Hydroxyethylcellulose: A na-enyekwa Hydroxyethylcellulose n'ụdị ntụ ntụ mana ọ na-agbaze ngwa ngwa na mmiri. Ọ dissolves na-etolite doro anya ma ọ bụ ubé turbid ngwọta, dabere na ịta na ndị ọzọ nhazi components.
4. Ngwongwo na-eme ka o sie ike:
Carbomer: Ndị na-emepụta ihe na-arụ ọrụ nke ọma ma nwee ike ịmepụta viscosity n'ụdị dịgasị iche iche, gụnyere ude, gels, na lotions. Ha na-enye ezigbo ihe nkwụsịtụ ma na-ejikarị eme ka emulsions guzosie ike.
Hydroxyethylcellulose: Hydroxyethylcellulose na-arụkwa ọrụ dị ka onye na-ebu ibu mana ọ na-egosipụta omume rheological dị iche ma e jiri ya tụnyere ndị carbomers. Ọ na-enye pseudoplastic ma ọ bụ shear-thinning eruba na usoro, nke pụtara na viscosity ya na-ebelata n'okpuru nrụgide shiee, na-eme ka ngwa ngwa dị mfe ma gbasaa.
5. ndakọrịta:
Carbomer: Carbomers dakọtara na ọtụtụ ihe ịchọ mma na ọkwa pH. Otú ọ dị, ha nwere ike ịchọ neutralization na alkalis (dịka, triethanolamine) iji nweta ezigbo thickening na gelling Njirimara.
Hydroxyethylcellulose: Hydroxyethylcellulose dakọtara na ihe mgbaze dị iche iche na ihe ịchọ mma nkịtị. Ọ kwụsiri ike n'elu oke pH sara mbara yana ọ dịghị achọ inyopụ anya maka ịgba.
6. Mpaghara Ngwa:
Carbomer: Carbomers na-ahụta ojiji nke ukwuu na ngwaahịa nlekọta onwe onye dị ka ude, lotions, gels, na usoro nlekọta ntutu. A na-ejikwa ha na ngwaahịa ọgwụ dị ka gels topical na ngwọta anya.
Hydroxyethylcellulose: Hydroxyethylcellulose bụ nke a na-arụkarị ọrụ na nhazi ịchọ mma na nlekọta onwe ya, gụnyere shampoos, conditioners, washs body, and toothpaste. A na-ejikwa ya na ngwa ọgwụ, karịsịa n'ụdị usoro.
7. Njirimara mmetụta:
Carbomer: Carbomer gels na-egosipụtakarị udidi dị nro ma na-atọ ụtọ, na-enye ahụmịhe mmetụta na-achọsi ike na nhazi. Otú ọ dị, ha nwere ike ịdị ntakịrị mkparị ma ọ bụ na-arapara n'ahụ na ngwa n'ọnọdụ ụfọdụ.
Hydroxyethylcellulose: Hydroxyethylcellulose na-enye mmetụta silky na enweghị nnyapade na nhazi. Omume ya na-akpụ akpụ na-enye aka na mgbasa ozi dị mfe na nnabata, na-eme ka ahụmịhe onye ọrụ dịkwuo elu.
8. Ntụle usoro iwu:
Carbomer: A na-amatakarị ndị na-ahụ maka ụgbọ ala dị ka nchekwa (GRAS) site n'aka ndị na-ahụ maka njikwa mgbe ejiri ya dịka usoro nrụpụta dị mma (GMP). Agbanyeghị, ihe achọrọ maka usoro iwu nwere ike ịdịgasị iche dabere na ngwa ezubere na mpaghara mpaghara.
Hydroxyethylcellulose: Hydroxyethylcellulose ka a na-ahụta na ọ dị mma maka ojiji na ihe ịchọ mma na ọgwụ, yana nkwado iwu sitere n'aka ndị ọchịchị dị mkpa. Nrube isi na ụkpụrụ na ntuziaka dị mkpa maka ịgba mbọ hụ na nchekwa ngwaahịa na arụmọrụ dị.
mgbe ma carbomer na hydroxyethylcellulose na-eje ozi dị ka irè thickeners na stabilizers dị iche iche formulations, ha dị iche iche na okwu nke chemical mejupụtara, molekụla Ọdịdị, solubility, ndim Njirimara, ndakọrịta, ngwa mpaghara, sensory e ji mara, na regulatory echiche. Ịghọta ndịiche ndị a dị oké mkpa maka ndị na-emepụta ihe ịhọrọ ihe kachasị mma maka ngwaahịa ha chọrọ na njirisi arụmọrụ ha.
Oge nzipu: Eprel-18-2024