Ọgwụ Excipient

Ọgwụ Excipient

Hydroxypropyl methylcellulose (HPMC) na-acha ọcha ma ọ bụ mmiri ara ehi na-acha ọcha, enweghị isi, enweghị ụtọ, ntụ ntụ ma ọ bụ granule, ọnwụ dị arọ na ihicha anaghị agafe 10%, soluble na mmiri oyi ma ọ bụghị mmiri ọkụ, nwayọọ nwayọọ na mmiri ọkụ Ọzịza, peptization, na akpụ a viscous colloidal ngwọta, nke na-aghọ ihe ngwọta mgbe jụrụ oyi, na-aghọ gel mgbe ọkụ.HPMC enweghị ike ịsacha na ethanol, chloroform na ether.Ọ bụ soluble na ngwakọta agwakọta nke methanol na methyl chloride.Ọ na-agbaze na ihe mgbaze agwakọta nke acetone, methyl chloride na isopropanol na ụfọdụ ihe mgbaze organic ndị ọzọ.Ngwọta mmiri ya nwere ike ịnabata nnu (ngwọta colloidal anaghị emebi nnu), na pH nke 1% mmiri mmiri bụ 6-8.Usoro molekụla nke HPMC bụ C8H15O8- (C10H18O6) -C815O, na mkpokọta molekul dị ihe dịka 86,000.

Pharmaceutical-Excipient

HPMC nwere ọmarịcha mmiri solubility na mmiri oyi.Enwere ike igbari ya n'ime ngwọta na-egbuke egbuke na obere edemede na mmiri oyi.N'ụzọ megidere nke ahụ, ọ bụ ihu ọma insoluble na mmiri ọkụ n'elu 60 ℃ na ike zaa naanị.Ọ bụ cellulose ether na-abụghị ionic.Ngwọta ya enweghị ụgwọ ionic, anaghị emekọrịta ya na salts metal ma ọ bụ ogige ionic organic, ma ọ dịghị emeghachi omume na ngwa ndị ọzọ n'oge usoro nkwadebe;o nwere ihe na-egbochi ihe nfụkasị ahụ siri ike, yana mmụba na ogo nke nnọchi n'ime usoro molekụla, ya Ọ na-eguzogide ọgwụ maka allergies ma kwụsie ike;ọ bụkwa metabolically inert.Dị ka ihe mgbakwunye ọgwụ, ọ naghị metabolized ma ọ bụ banye n'ime ya.Ya mere, ọ naghị enye calorie na ọgwụ na nri.Ọ bụ obere kalori, enweghị nnu, na enweghị nnu maka ndị na-arịa ọrịa shuga.Ọgwụ Allergenic na nri nwere ihe pụrụ iche;ọ bụ ihe kwụsiri ike na acids na alkalis, ma ọ bụrụ na uru PH karịrị 2 ~ 11 ma na-emetụta okpomọkụ dị elu ma ọ bụ nwee ogologo oge nchekwa, viscosity ya ga-ebelata;ngwọta mmiri ya nwere ike inye ọrụ Surface, na-egosi esemokwu elu na-agafeghị oke na esemokwu interfacial;ọ nwere emulsification dị irè na usoro abụọ nke abụọ, enwere ike iji ya mee ihe dị ka onye na-eme ka ọ dị mma na colloid nchebe;ngwọta mmiri ya nwere ihe ndị na-emepụta ihe nkiri dị mma, ọ bụ mbadamba nkume na pill A ezigbo mkpuchi ihe.Ihe mkpuchi ihe nkiri a na-emepụta site na ya nwere uru nke enweghị agba na ike.Ịgbakwunye glycerin nwekwara ike imeziwanye plasticity ya.

Ngwaahịa QualiCell HPMC nwere ike imeziwanye site na akụrụngwa ndị a na Pharmaceutical Excipient:
· Ozugbo soluble na mmiri na volatilized site mgbaze, HPMC na-eme transperent film na elu tensile ike.
· Na-akwalite ike njikọ.
Matriks hydrophilic ejiri ya na HPMC hydrates mepụta akwa gel, na-achịkwa ụkpụrụ mwepụta ọgwụ.

Kwadoro ọkwa: Rịọ TDS
HPMC 60E5 pịa ebe a
HPMC 60E15 pịa ebe a