Kedu ihe a na-eji hypromellose na mbadamba?

Hypromellose, nke a makwaara dị ka hydroxypropyl methylcellulose (HPMC), na-ejikarị eme ihe na mbadamba mbadamba maka ọtụtụ ebumnuche:

1. Ihe nchikota: A na-ejikarị HPMC eme ihe dị ka ihe nchikota n'ụdị mbadamba nkume iji jide ihe ndị na-emepụta ọgwụ na-arụ ọrụ (API) na ihe ndị ọzọ na-enye ọnụ.Dị ka ihe nkedo, HPMC na-enyere aka ịmepụta mbadamba nkume jikọtara ọnụ nke nwere ike ọrụ zuru oke, na-ahụ na mbadamba nkume ahụ na-ejigide iguzosi ike n'ezi ihe n'oge njikwa, nkwakọ ngwaahịa na nchekwa.
2. Disintegrant: Na mgbakwunye na ihe njide ya, HPMC nwekwara ike ịrụ ọrụ dị ka ihe na-agbasa na mbadamba.Ndị na-agbasasị na-enyere aka ịkwalite mgbawa ngwa ngwa ma ọ bụ nkewa nke mbadamba nkume mgbe ị risịrị nri, na-eme ka mwepụta ọgwụ na ịmịnye n'ime eriri afọ.HPMC na-aza ngwa ngwa mgbe a na-ejikọta ya na mmiri, na-eduga na mgbawa nke mbadamba nkume n'ime obere irighiri ihe na inye aka na mgbasa ọgwụ.
3. Ihe nkiri bụbu/onye na-ekpuchi mkpuchi: Enwere ike iji HPMC dị ka onye na-emepụta ihe nkiri ma ọ bụ ihe mkpuchi maka mbadamba.Mgbe etinyere ya dị ka ihe nkiri dị mkpa n'elu mbadamba nkume, HPMC na-enyere aka melite ọdịdị, ilo, na nkwụsi ike nke mbadamba.Ọ nwekwara ike ịbụ ihe mgbochi iji kpuchido mbadamba nkume ahụ pụọ na mmiri mmiri, ọkụ, na ikuku ikuku, si otú a na-eme ka ndụ ndụ dịkwuo mma na ichekwa ike nke ọgwụ ahụ.
4. Matrix bụbu: N'ime usoro mbadamba ihe na-achịkwa ma ọ bụ ntọhapụ, a na-ejikarị HPMC eme ihe dị ka matriks mbụ.Dị ka matriks nke mbụ, HPMC na-achịkwa ntọhapụ nke ọgwụ ahụ site n'ịmepụta gel-dị ka matrix gburugburu API, na-achịkwa ọnụego ntọhapụ ya ruo ogologo oge.Nke a na-enye ohere maka nnyefe ọgwụ na-achịkwa ma melite nnabata onye ọrịa site n'ibelata ugboro ugboro nke doses.
5. Excipient: HPMC nwekwara ike iji dị ka ihe mgbakwunye na mbadamba mbadamba iji gbanwee njirimara nke mbadamba nkume, dị ka ike ike, friability na ọnụego mgbasa.Ngwongwo ya dị iche iche na-eme ka ọ dị mma maka ojiji n'ụdị dị iche iche, gụnyere mwepụta ozugbo, nkwụsị oge, na mbadamba mwepụta agbatị.

N'ozuzu, HPMC bụ ihe a na-eji ọgwụ eme ihe n'ụdị mbadamba nkume n'ihi ike ya dị iche iche, ọdịdị ya, na ịdị irè n'inweta akụrụngwa mbadamba ihe achọrọ.Ya multifunctional ọdịdị na-enye ohere formulators ịkwa akwa mbadamba iji izute kpọmkwem ọgwụ nnyefe chọrọ na ndidi mkpa.