Kedu ihe a na-eji hypromellose na mbadamba?

Hypromellose, nke a makwaara dị ka hydroxypropyl methylcellulose (HPMC), na-ejikarị eme ihe na mbadamba mbadamba maka ọtụtụ ebumnuche:

1. Ihe nchikota: A na-ejikarị HPMC eme ihe dị ka ihe nchikota n'ụdị mbadamba nkume iji jide ihe ndị na-emepụta ọgwụ na-arụ ọrụ (API) na ihe ndị ọzọ na-enye ọnụ. Dị ka ihe nkedo, HPMC na-enyere aka ịmepụta mbadamba nkume jikọtara ọnụ nke nwere ike ọrụ zuru oke, na-ahụ na mbadamba nkume ahụ na-ejigide iguzosi ike n'ezi ihe n'oge njikwa, nkwakọ ngwaahịa na nchekwa.
2. Disintegrant: Na mgbakwunye na ihe njide ya, HPMC nwekwara ike ịrụ ọrụ dị ka ihe na-agbasa na mbadamba. Ndị na-agbasasị na-enyere aka ịkwalite mgbawa ngwa ngwa ma ọ bụ nkewa nke mbadamba nkume mgbe ị risịrị nri, na-eme ka mwepụta ọgwụ na ịmịnye n'ime eriri afọ. HPMC na-aza ngwa ngwa mgbe a na-ejikọta ya na mmiri, na-eduga na mgbawa nke mbadamba nkume n'ime obere irighiri ihe na inye aka na mgbasa ọgwụ.
3. Ihe nkiri bụbu / onye na-ekpuchi mkpuchi: Enwere ike iji HPMC dị ka onye na-emepụta ihe nkiri ma ọ bụ ihe mkpuchi maka mbadamba. Mgbe etinyere ya dị ka ihe nkiri dị mkpa n'elu mbadamba nkume, HPMC na-enyere aka melite ọdịdị, ilo, na nkwụsi ike nke mbadamba. Ọ nwekwara ike ịbụ ihe mgbochi iji kpuchido mbadamba nkume ahụ pụọ na mmiri mmiri, ọkụ, na ikuku ikuku, si otú a na-eme ka ndụ ndụ dịkwuo mma na ichekwa ike nke ọgwụ ahụ.
4. Matrix bụbu: N'ime usoro mbadamba ihe na-achịkwa ma ọ bụ ntọhapụ, a na-ejikarị HPMC eme ihe dị ka matriks mbụ. Dị ka matriks nke mbụ, HPMC na-achịkwa ntọhapụ nke ọgwụ ahụ site n'ịmepụta gel-dị ka matrix gburugburu API, na-achịkwa ọnụego ntọhapụ ya ruo ogologo oge. Nke a na-enye ohere maka nnyefe ọgwụ na-achịkwa ma melite nnabata onye ọrịa site n'ibelata ugboro ugboro nke doses.
5. Excipient: HPMC nwekwara ike iji dị ka ihe mgbakwunye na mbadamba mbadamba iji gbanwee njirimara nke mbadamba nkume, dị ka ike ike, friability na ọnụego mgbasa. Ngwongwo ya dị iche iche na-eme ka ọ dị mma maka ojiji n'ụdị dị iche iche, gụnyere mwepụta ozugbo, nkwụsị oge, na mbadamba mwepụta agbatị.

N'ozuzu, HPMC bụ ihe a na-eji ọgwụ eme ihe n'ụdị mbadamba nkume n'ihi ike ya dị iche iche, ọdịdị ya, na ịdị irè n'inweta akụrụngwa mbadamba ihe achọrọ. Ya multifunctional ọdịdị na-enye ohere formulators ịkwa akwa mbadamba iji izute kpọmkwem ọgwụ nnyefe chọrọ na ndidi mkpa.