Ọkwa ọgwụ HPMC
Pharmaceutical ọkwa HPMCHydroxypropyl methylcellulose na-acha ọcha ma ọ bụ mmiri ara ehi na-acha ọcha, enweghị isi, enweghị ụtọ, ntụ ntụ ma ọ bụ granule, ọnwụ dị arọ na ihicha adịghị agafe 10%, soluble na mmiri oyi ma ọ bụghị mmiri ọkụ, nwayọọ nwayọọ na mmiri ọkụ Ọzịza, peptization, na-akpụ a viscous colloidal ngwọta. , nke na-aghọ ihe ngwọta mgbe ọ dị jụụ, na-aghọ gel mgbe ọkụ.HPMC enweghị ike ịsacha na ethanol, chloroform na ether.Ọ bụ soluble na ngwakọta agwakọta nke methanol na methyl chloride.Ọ na-agbaze na ihe mgbaze agwakọta nke acetone, methyl chloride na isopropanol na ụfọdụ ihe mgbaze organic ndị ọzọ.Ngwọta mmiri ya nwere ike ịnabata nnu (ngwọta colloidal anaghị emebi nnu), na pH nke 1% mmiri mmiri bụ 6-8.Usoro molekụla nke HPMC bụ C8H15O8- (C10H18O6) -C815O, na mkpokọta molekul dị ihe dịka 86,000.
Nkọwa kemịkalụ
| PHPMC na-emerụ ahụ Nkọwapụta | HPMC60E( 2910) | HPMC65F( 2906) | HPMC75K( 2208) |
| Gel okpomọkụ (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (cps, 2% Ngwọta) | 3, 5, 6, 15, 50,100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Ọkwa ngwaahịa:
| PHPMC na-emerụ ahụ Nkọwapụta | HPMC60E( 2910) | HPMC65F( 2906) | HPMC75K( 2208) |
| Gel okpomọkụ (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (cps, 2% Ngwọta) | 3, 5, 6, 15, 50,100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Ngwa
| PharmaIhe mgbakwunyeNgwa | Pharmaceutical Gnke HPMC | Usoro onunu ogwu |
| Nnukwu Laxative | 75K4000,75K100000 | 3-30% |
| Ude, gel | 60E4000,75K4000 | 1-5% |
| Nkwadebe anya | 60E4000 | 01.-0.5% |
| Nkwadebe Mbelata Anya | 60E4000 | 0.1-0.5% |
| Onye nnọchi anya nkwusioru | 60E4000, 75K4000 | 1-2% |
| Antacids | 60E4000, 75K4000 | 1-2% |
| Mbadamba mbadamba ihe | 60E5, 60E15 | 0.5-5% |
| Mgbakọ Wet granulation | 60E5, 60E15 | 2-6% |
| Ihe mkpuchi mbadamba | 60E5, 60E15 | 0.5-5% |
| Matrix mwepụta a na-achịkwa | 75K100000,75K15000 | 20-55% |
Atụmatụ na uru:
HPMC nwere ọmarịcha mmiri solubility na mmiri oyi.Enwere ike igbari ya n'ime ngwọta na-egbuke egbuke na obere edemede na mmiri oyi.N'ụzọ megidere nke ahụ, ọ bụ ihe a na-apụghị imeri emeri na mmiri ọkụ karịa 60℃na nwere ike na-aza naanị.Ọ bụ cellulose ether na-abụghị ionic.Ngwọta ya enweghị ụgwọ ionic, anaghị emekọrịta ya na salts metal ma ọ bụ ogige ionic organic, na anaghị emeghachi omume na ngwa ndị ọzọ n'oge usoro nkwadebe;ọ nwere ike mgbochi uche, na dị ka ogo nke nnọchi na molekụla Ọdịdị na-abawanye, ya Ọ bụ ihe na-eguzogide ọgwụ na allergies na ọzọ kwụsie ike;ọ bụkwa metabolically inert.Dị ka ihe mgbakwunye ọgwụ, ọ naghị metabolized ma ọ bụ banye n'ime ya.Ya mere, ọ naghị enye okpomọkụ na ọgwụ na nri.Ọ nwere obere kalori, enweghị nnu, na enweghị nnu maka ndị ọrịa mamịrị.Ọgwụ Allergenic na nri nwere ihe pụrụ iche;ọ bụ ihe kwụsiri ike na acids na alkalis, ma ọ bụrụ na uru PH karịrị 2 ~ 11 ma na-emetụta okpomọkụ dị elu ma ọ bụ nwee ogologo oge nchekwa, viscosity ya ga-ebelata;ngwọta mmiri ya nwere ike inye ọrụ Surface, na-egosi esemokwu elu na-agafeghị oke na ụkpụrụ esemokwu interfacial;ọ nwere emulsification dị irè na usoro abụọ nke abụọ, enwere ike iji ya dị ka onye na-eme ka ọ dị mma na colloid nchebe;ngwọta mmiri ya nwere ihe ndị na-emepụta ihe nkiri magburu onwe ya, ọ bụkwa mbadamba nkume na pill A ezigbo mkpuchi ihe.Ihe mkpuchi ihe nkiri a na-emepụta site na ya nwere uru nke enweghị agba na ike.Ịgbakwunye glycerin nwekwara ike imeziwanye plasticity ya.
Nkwakọ ngwaahịa
TỌ ọkọlọtọ mbukota bụ 25kg /Fiberdrum
20'FCL: 9 ton nwere palletized;10 ton enweghị palleted.
40'FCL:18ton na palletized;20ton enweghị palletized.
Nchekwa:
Chekwaa ya n'ebe dị jụụ, kpọrọ nkụ n'okpuru 30 Celsius C ma chebe ya pụọ na iru mmiri na ịpị, ebe ọ bụ na ngwongwo ahụ bụ thermoplastic, oge nchekwa ekwesịghị gafere ọnwa 36.
ndetu nchekwa:
Ihe data a dị n'elu kwekọrọ na ihe ọmụma anyị, mana ahapụla ndị ahịa ahụ nke ọma na-enyocha ya ozugbo na nnata.Iji zere ụdị dị iche iche na akụrụngwa dị iche iche, biko mee nyocha karịa tupu iji ya.
Oge nzipu: Jan-01-2024