A na-ahụta Carboxymethylcellulose (CMC) dị mma maka iji ya na ụlọ ọrụ dị iche iche, gụnyere nri na mpaghara ọgwụ, ebe a na-arụ ya nke ukwuu.Mwepụta cellulose a nwere soluble mmiri emeela nnwale na nyocha siri ike iji hụ na nchekwa ya maka ahụike mmadụ na gburugburu ebe obibi.Na mkparịta ụka a zuru oke, anyị na-abanye n'ime akụkụ nchekwa nke carboxymethylcellulose, na-enyocha ọnọdụ nchịkwa ya, mmetụta ahụike nwere ike ime, echiche gburugburu ebe obibi, na nchọpụta nyocha dị mkpa.
Ọnọdụ nchịkwa:
A kwadoro Carboxymethylcellulose maka ndị ọrụ nchịkwa gburugburu ụwa.Na United States, nchịkwa nri na ọgwụ ọjọọ (FDA) na-ahọpụta CMC dị ka ihe a na-anabatakarị dị ka ihe nchekwa (GRAS) mgbe ejiri ya dịka usoro nrụpụta dị mma.N'otu aka ahụ, European Safety Authority (EFSA) enyochala CMC wee guzobe ụkpụrụ oriri kwa ụbọchị (ADI), na-akwado nchekwa ya maka oriri.
Na ọgwụ na ihe ịchọ mma, a na-eji CMC eme ihe n'ọtụtụ ebe, na nchekwa ya na-eguzobe site na nrube isi na ụkpụrụ nduzi.Ọ na-agbaso ụkpụrụ pharmacopeial, na-ahụ na ọ dabara adaba maka ojiji na usoro ọgwụ.
Nchekwa na ngwaahịa nri:
1. Ọmụmụ ihe gbasara toxicological:
A na-eme nchọpụta toxicological dị ukwuu iji chọpụta nchekwa nke CMC.Ọmụmụ ihe ndị a gụnyere nyocha nke nnukwu na-adịghị ala ala toxicity, mutagenicity, carcinogenicity, na ịmụ nwa na mmepe toxicity.Nsonaazụ na-akwado nchekwa nke CMC n'ime ọkwa ojiji emebere.
2. Nri kwa ụbọchị anabatara (ADI):
Ndị na-ahụ maka nchịkwa na-edobe ụkpụrụ ADI iji guzobe ọnụọgụ nke ihe enwere ike iri kwa ụbọchị n'ogologo ndụ na-enweghị ihe egwu ahụike bara uru.CMC nwere ADI guzosie ike, na ojiji ya na ngwaahịa nri dị n'okpuru ọkwa ndị a na-ewere dị ka nchekwa.
3. Ihe nfụkasị ahụ:
A na-ewerekarị CMC dị ka ọ bụghị ihe nfụkasị ahụ.Allergies na CMC dị ụkọ nke ukwuu, na-eme ka ọ bụrụ ihe dị mma maka ndị nwere mmetụta dị iche iche.
4. Ike mgbari:
CMC anaghị agbaze ma ọ bụ banye n'ime eriri afọ mmadụ.Ọ na-agafe sistemu nri nri anaghị agbanwe agbanwe, na-enye aka na profaịlụ nchekwa ya.
Nchekwa na Pharmaceuticals na ịchọ mma:
1. Biocompatibility:
N'ime usoro ọgwụ na ịchọ mma, a na-eji CMC akpọrọ ihe maka ịdị ndụ ya.A na-anabata ya nke ọma site na akpụkpọ anụ na akpụkpọ anụ mucous, na-eme ka ọ dị mma maka iji mee ihe n'ụdị dị iche iche na ngwa ọnụ.
2. Nkwụsi ike:
CMC na-enye aka na nkwụsi ike nke usoro ọgwụ, na-enyere aka ịnọgide na-eguzosi ike n'ezi ihe na ịdị irè nke ọgwụ.Ojiji ya juru ebe niile na nkwusioru ọnụ, ebe ọ na-enyere aka igbochi idozi irighiri ihe siri ike.
3. Ngwa anya:
A na-ejikarị CMC eme ihe na ngwọta anya na ọdịda anya n'ihi ike ya na-abawanye viscosity, welie njigide anya, na melite irè ọgwụgwọ nke nhazi ahụ.A na-akwado nchekwa ya na ngwa ndị a site na ogologo akụkọ ihe mere eme ya.
Ihe gbasara gburugburu:
1. Mmebi ndụ:
Carboxymethylcellulose sitere na isi mmalite cellulose sitere n'okike ma na-emebi emebi.Ọ na-enweta ire ere site na microorganisms na gburugburu ebe obibi, na-enye aka na profaịlụ gburugburu ebe obibi ya.
2. Nsi nke mmiri:
Nnyocha na-enyocha nsí mmiri nke CMC egosiwo n'ozuzu nsí dị ala nye ihe ndị dị n'ime mmiri.Eji ya mee ihe n'ụdị mmiri, dị ka agba na ncha, adịghị ejikọta ya na nnukwu nsogbu gburugburu ebe obibi.
Nchọpụta Nchọpụta na Ọdịmma Na-apụta:
1. Isi mmalite na-adịgide adịgide:
Ka ọchịchọ maka ihe na-adịgide adịgide na gburugburu ebe obibi na-eto eto, a na-enwewanye mmasị n'ịchọta ngwa ngwa maka mmepụta CMC.Nchọpụta lekwasịrị anya n'ịkwalite usoro mmịpụta na ịchọpụta isi mmalite cellulose ọzọ.
2. Ngwa Nanocellulose:
Nnyocha na-aga n'ihu na-enyocha iji nanocellulose, nke sitere na isi mmalite cellulose gụnyere CMC, na ngwa dị iche iche.Nanocellulose na-egosipụta akụrụngwa pụrụ iche ma nwee ike ịchọta ngwa na mpaghara dịka nanotechnology na nyocha biomedical.
Mmechi:
Carboxymethylcellulose, ya na profaịlụ nchekwa ya guzosiri ike, bụ isi ihe dị na ụlọ ọrụ dị iche iche, gụnyere nri, ọgwụ, ihe ịchọ mma, textiles, na ndị ọzọ.Nkwenye usoro iwu, ihe ọmụmụ toxicological buru ibu, na akụkọ ihe mere eme nke iji nchekwa na-akwado na ọ dabara maka ngwa dị iche iche.Ka ụlọ ọrụ na-aga n'ihu na-etolite, nchekwa na nkwado nke ihe bụ ihe kachasị mkpa, na carboxymethylcellulose kwekọrọ na usoro ndị a.
Ọ bụ ezie na a na-ewerekarị CMC dị ka nchekwa, ndị nwere ụdị allergies ma ọ bụ mmetụta uche kwesịrị ịkpọtụrụ ndị ọkachamara ahụike ma ọ bụ ndị na-ahụ maka ahụ ike ma ọ bụrụ na ha nwere nchegbu gbasara ojiji ya.Ka ọganihu nyocha na ngwa ọhụrụ na-apụta, mmekorita na-aga n'ihu n'etiti ndị nchọpụta, ndị na-emepụta ihe, na ndị na-ahụ maka nhazi ga-ahụ na CMC na-aga n'ihu na-ezute ụkpụrụ kachasị elu nke nchekwa na ịdị irè.Na nchịkọta, carboxymethylcellulose bụ ihe dị mma na nke bara uru na-enye aka na arụmọrụ na ịdịmma nke ọtụtụ ngwaahịa, na-arụ ọrụ dị mkpa na ngwa dịgasị iche iche n'ofe ahịa ụwa.
Oge nzipu: Jan-04-2024