Ọnụ ahịa n'ùkwù 2019 Akwa mkpuchi ọgwụ dị elu yana onye nnọchi anya mwepụta a na-achịkwa
N'ịnọgide maka echiche nke "Ịmepụta ngwaahịa nke kachasị mma na ịmepụta enyi na ndị mmadụ taa si gburugburu ụwa", anyị na-etinye ọchịchọ nke ndị na-azụ ahịa mgbe niile ka ha malite maka 2019 n'ùkwù ọnụahịa Advanced Drug Coating and Controlled Release Agent, Anyị na-enwekwa mgbe niile. na-achọ ịmalite mmekọrịta na ndị na-ebubata ọhụrụ iji nye ngwọta ọhụrụ na smart maka ndị ahịa anyị bara uru.
N'ịnọgide maka nghọta nke "Ịmepụta ngwaahịa ndị kachasị mma na ịmepụta enyi na ndị mmadụ taa si gburugburu ụwa", anyị na-etinye ọchịchọ nke ndị na-azụ ahịa na-amalite mgbe niile.Pharmacoat HPMC, Anyị na-esi ọnwụ na ụkpụrụ nke "Ebe E Si Nweta ịbụ isi, Ahịa ịbụ eze na Quality ịbụ ndị kasị mma", anyị na-na-na-na-na-atụ anya na ibe imekọ ihe ọnụ na ndị enyi niile nọ n'ụlọ na ná mba ọzọ na anyị na-aga ike a na-egbuke egbuke n'ọdịnihu nke azụmahịa.
Nkọwa ngwaahịa
Hydroxypropyl Methyl Cellulose (HPMC)
Usoro ihe omimi
Hypromellose (Hydroxypropylmethylcellulose: HPMC) ngbanwe ụdị 2910, 2906, 2208 (USP)
Njirimara anụ ahụ
- ntụ ntụ ọcha ọcha ma ọ bụ odo odo
- Soluble na ngwakọta organic ma ọ bụ ihe mgbaze mmiri
- Ime elu transperent film mgbe mgbaze wepụ
- Enweghị mmeghachi omume kemịkalụ na ọgwụ n'ihi ihe na-abụghị ionic ya
- Arọ Molecular: 10,000 ~ 1,000,000
Gel ntụpọ: 40 ~ 90 ℃
- Ebe mgbanye onwe: 360 ℃
Hydroxypropyl Methylcellulose (HPMC) Pharmaceutical Grade bụ Hypromellose ọgwụ excipient na mgbakwunye, nke a pụrụ iji dị ka thickener, dispersant, emulsifier na-akpụ ihe nkiri.
QualiCell Cellulose ether mejupụtara methyl cellulose (USP, EP,BP,CP) na atọ nnọchi ụdị hydroxypropyl methyl cellulose (hypromellose USP, EP,BP,CP) ọ bụla dị na ọtụtụ akara ule dị iche iche na viscosity.HPMC ngwaahịa na-ewepụtara si eke nụchara anụcha. Owu-owu na pulp osisi, na-emezu ihe niile achọrọ nke USP, EP, BP, yana asambodo Kosher na Halal.
N'ime usoro mmepụta ihe, a na-eji methyl chloride na-eme ka owu eke sachara nke ukwuu ma ọ bụ jikọtara ya na methyl chloride na propylene oxide iji mepụta ether cellulose na-agbaze mmiri na-abụghị ionic. Ọ dịghị anụmanụ ihe onwunwe na-eji na mmepụta nke HPMC.HPMC nwere ike iji dị ka ihe nkedo maka siri ike onunu ogwu ụdị dị ka mbadamba nkume na granules. Ọ na-arụkwa ọrụ dị iche iche, dịka ọmụmaatụ, n'ịkwalite njide mmiri, ịgbatị, na-eme dị ka colloid nchebe n'ihi ọrụ elu ya, na-akwado ntọhapụ, na mmepụta ihe nkiri.
QualiCell HPMC na-enye ọrụ dị iche iche dị ka njide mmiri, colloid nchebe, ọrụ elu, ntọhapụ na-adịgide adịgide. Ọ bụ ngwakọta na-abụghị ionic na-eguzogide nnu ma kwụsie ike karịa pH-n'obosara. Ngwa ngwa nke HPMC bụ ihe nchikota maka ụdị ọgwụgwọ siri ike dị ka mbadamba nkume na granules ma ọ bụ thickener maka ngwa mmiri mmiri.
Pharma HPMC na-abịa na viscosity dịgasị iche iche sitere na 3 ruo 200,000 cps, yana enwere ike iji ya mee ihe maka mkpuchi mbadamba, granulation, ihe nkedo, thickener, stabilizer na ime capsule HPMC akwukwo nri.
Nkọwa kemịkalụ
Hypromellose Nkọwapụta | 60E (2910) | 65F (2906) | 75K (2208) |
Gel okpomọkụ (℃) | 58-64 | 62-68 | 70-90 |
Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
Viscosity (cps, 2% Ngwọta) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 |
Ọkwa ngwaahịa
Hypromellose Nkọwapụta | 60E (2910) | 65F (2906) | 75K (2208) |
Gel okpomọkụ (℃) | 58-64 | 62-68 | 70-90 |
Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
Viscosity (cps, 2% Ngwọta) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 |
Ngwa
Pharma Grade HPMC na-eme ka mmepụta nke usoro mwepụta a na-achịkwa ya na ịdị mma nke usoro ijikọ mbadamba nkume a na-ejikarị eme ihe. Pharma Grade na-enye ezigbo ntụ ntụ, ịdị n'otu, na mkpakọ, na-eme ka ha dabara nke ọma maka mkpakọ ozugbo.
Ngwa ngwa mgbakwunye ọgwụ | Pharma ọkwa HPMC | Usoro onunu ogwu |
Nnukwu Laxative | 75K4000,75K100000 | 3-30% |
Ude, gel | 60E4000,75K4000 | 1-5% |
Nkwadebe anya | 60E4000 | 01.-0.5% |
Nkwadebe Mbelata Anya | 60E4000 | 0.1-0.5% |
Onye nnọchi anya nkwusioru | 60E4000, 75K4000 | 1-2% |
Antacids | 60E4000, 75K4000 | 1-2% |
Mbadamba mbadamba ihe | 60E5, 60E15 | 0.5-5% |
Mgbakọ Wet granulation | 60E5, 60E15 | 2-6% |
Ihe mkpuchi mbadamba | 60E5, 60E15 | 0.5-5% |
Matrix mwepụta a na-achịkwa | 75K100000,75K15000 | 20-55% |
Atụmatụ na uru
- Na-eme ka njirimara eruba ngwaahịa
- Na-ebelata oge nhazi
- Profaịlụ mgbasa nke yiri, kwụsiri ike
- Na-akwalite ịdị n'otu ọdịnaya
- Na-ebelata ọnụ ahịa mmepụta
- Na-ejigide ike tensile mgbe usoro mkpirisi okpukpu abụọ (mkpọkọ mpịakọta).
Nkwakọ ngwaahịa
Nkwakọ ọkọlọtọ bụ 25kg / drum
20'FCL: 9 ton nwere palletized; 10 ton enweghị palleted.
40'FCL: 18 ton nwere palletized; 20 ton unpalletized. N'ịnọgide maka echiche nke "Ịmepụta ngwaahịa nke kachasị mma na ịmepụta enyi na ndị mmadụ taa si n'ụwa nile", anyị na-etinyekarị ọchịchọ nke ndị na-azụ ahịa na-amalite na 2019 n'ogbe ọnụ Advanced Drug mkpuchi na Controlled Release Agent, Anyị na-achọkwa ka anyị na ndị na-ebubata ngwaahịa ọhụrụ na-emekọrịta ihe iji nye ndị ahịa anyị ji kpọrọ ihe ngwọta ọhụrụ na smart.
Ọnụ ahịa n'ogbe 2019Pharmacoat HPMC, Anyị na-esi ọnwụ na ụkpụrụ nke "Ebe E Si Nweta ịbụ isi, Ahịa ịbụ eze na Quality ịbụ ndị kasị mma", anyị na-na-na-na-na-atụ anya na ibe imekọ ihe ọnụ na ndị enyi niile nọ n'ụlọ na ná mba ọzọ na anyị na-aga ike a na-egbuke egbuke n'ọdịnihu nke azụmahịa.