Hydroxypropyl Methyl Cellulose (HPMC), nke aha ahia a makwaara hypromellose, bụ polymer sịntetik sitere na cellulose eke. Isi mmalite nke cellulose maka mmepụta nke HPMC bụ osisi pulp ma ọ bụ owu. Usoro n'ichepụta gụnyere kemịkalụ gbanwee cellulose site na etherification, iwebata hydroxypropyl na methyl otu n'ime ọkpụkpụ azụ cellulose.

Mmepụta nke HPMC gụnyere ọtụtụ usoro:

1. Mwepụta cellulose:
   • A na-enweta cellulose site na isi ihe ọkụkụ, bụ isi osisi pulp ma ọ bụ owu. A na-ewepụta cellulose ahụ ma sachaa ya ka ọ bụrụ mkpụrụ osisi cellulose.
2. Alkalization:
   • A na-eji ngwọta alkaline na-emeso pulp cellulose, nke na-abụkarị sodium hydroxide (NaOH), iji mee ka ìgwè hydroxyl dị na agbụ cellulose rụọ ọrụ.
3. Etherification:
   • Etherification bụ isi nzọụkwụ na mmepụta nke HPMC. A na-emeghachi cellulose alkalized na propylene oxide (maka otu hydroxypropyl) na methyl chloride (maka otu methyl) iji webata otu ether ndị a na ọkpụkpụ azụ cellulose.
4. Nnọpụiche na ịsa:
   • Ihe si na cellulose emezigharịrị, nke bụ ugbu a Hydroxypropyl Methyl Cellulose, na-enweta usoro nkwụsịtụ iji wepụ alkali ọ bụla fọdụrụnụ. Mgbe ahụ, a na-asacha ya nke ọma iji kpochapụ ihe ndị na-adịghị ọcha na ihe ndị na-emepụta ihe.
5. ihicha na igwe igwe:
   • A na-akpọnwụ cellulose a gbanwere ka ọ wepụ oke mmiri wee gwerie ya n'ime ezigbo ntụ ntụ. Enwere ike ịchịkwa nha urughuru dabere na ngwa a chọrọ.

Ngwaahịa HPMC si na ya pụta bụ ntụ ntụ ọcha ma ọ bụ na-acha ọcha nwere ogo dị iche iche nke hydroxypropyl na nnọchi methyl. Njirimara akọwapụtara nke HPMC, dị ka solubility ya, viscosity, na njirimara arụmọrụ ndị ọzọ, dabere na ogo nnọchi na usoro nrụpụta.

Ọ dị mkpa iburu n'obi na HPMC bụ polymer synthetic semi-synthetic, na ọ bụ ezie na ọ sitere na cellulose eke, ọ na-enweta mgbanwe mgbanwe kemịkalụ dị ịrịba ama n'oge a na-emepụta ihe iji nweta ihe ndị a chọrọ maka ngwa ụlọ ọrụ dị iche iche.