Hydroxypropylmethylcellulose (HPMC) bụ mmepụta cellulose nke a na-ejikarị n'ọtụtụ ụlọ ọrụ, gụnyere ọgwụ, ihe owuwu na nri. Viscosity ya nwere ike ịdịgasị iche dabere n'ihe ndị dị ka ịdị arọ molekụla ya, ogo nnọchi anya ya, na itinye uche ngwọta.
Okwu Mmalite nke Hydroxypropyl Methylcellulose (HPMC)
Hydroxypropyl methylcellulose bụ polymer synthetic ọkara nke enwetara site na mgbanwe kemịkalụ nke cellulose. N'ihi ihe ndị pụrụ iche ya, a na-eji ya dị ka onye na-agba ume, onye na-ahụ maka gelling, ihe nkiri mbụ na stabilizer na ngwa dị iche iche.
Ọdịdị molecular na mejupụtara
HPMC nwere ọkpụkpụ azụ cellulose nwere hydroxypropyl na methoxy nọchiri anya ya. Ogo nke nnọchi (DS) na-ezo aka na nkezi ọnụọgụ nke ihe ngbanwe kwa otu anhydroglucose n'ime yinye cellulose. Uru DS a kapịrị ọnụ na-emetụta njirimara anụ ahụ na kemịkal nke HPMC.
HPMC viscosity
Viscosity bụ ihe dị mkpa maka HPMC, ọkachasị na ngwa ndị na-eji ihe na-eme ka ọ sie ike na gelling.
The viscosity nke HPMC ngwọta na-emetụta ọtụtụ ihe:
1. Arọ molekụla
The molekụla arọ nke HPMC na-emetụta ya viscosity. N'ozuzu, HPMC dị arọ dị elu na-emepụta ngwọta viscosity dị elu. Enwere akara ule HPMC dị iche iche n'ahịa, nke ọ bụla nwere oke ibu arọ nke ya.
2. Degree nke nnọchi (DS)
Ụkpụrụ DS nke hydroxypropyl na methoxy dị iche iche na-emetụta solubility na viscosity nke HPMC. Ụkpụrụ DS dị elu n'ozuzu na-ebute mmụba mmiri solubility na ngwọta ndị siri ike.
3. Ntinye uche
Ntinye uche nke HPMC na ngwọta bụ isi ihe na-emetụta viscosity. Ka itinye uche na-abawanye, viscosity na-abawanye. A na-akọwakarị mmekọrịta a site na nhata Krieger-Dougherty.
4. Okpomọkụ
Okpomọkụ na-emetụtakwa viscosity nke ngwọta HPMC. N'ikwu okwu n'ozuzu, viscosity na-ebelata ka okpomọkụ na-abawanye.
Mpaghara ngwa
Ọgwụ: A na-ejikarị HPMC eme ihe na usoro ọgwụ, gụnyere mbadamba na ngwọta anya, ebe ntọhapụ na-achịkwa na viscosity dị oke mkpa.
Mwube: N'ime ụlọ ọrụ na-ewu ụlọ, a na-eji HPMC eme ihe dị ka ihe na-esi ísì ụtọ na ngwaahịa simenti iji meziwanye ọrụ na njide mmiri.
Ụlọ ọrụ nri: A na-eji HPMC eme ihe dị ka thickener, stabilizer na emulsifier na ngwa nri.
Viscosity nke hydroxypropyl methylcellulose bụ ihe dị mgbagwoju anya na-emetụta ọtụtụ ihe dị ka ịdị arọ molekụla, ogo nke nnọchi, itinye uche na okpomọkụ. Ọkwa dị iche iche nke HPMC dị ka dabara ngwa ngwa, ndị na-emepụta na-enye mpempe akwụkwọ teknụzụ teknụzụ na-akọwapụta viscosity nso nke ọkwa ọ bụla n'okpuru ọnọdụ dị iche iche. Ndị na-eme nchọpụta na ndị na-emepụta ihe kwesịrị ịtụle ihe ndị a iji hazie ihe onwunwe nke HPMC iji mezuo ihe achọrọ nke ngwa ha chọrọ.
Oge nzipu: Jan-20-2024