Imepụta Hydroxypropyl Methylcellulose (HPMC) gụnyere ọtụtụ usoro dị mgbagwoju anya nke na-agbanwe cellulose ka ọ bụrụ polymer vasatail nwere ọtụtụ ngwa na ụlọ ọrụ dị iche iche. Usoro a na-amalitekarị site na mmịpụta cellulose sitere na isi mmalite nke osisi, na-esote mgbanwe kemịkalụ iji webata hydroxypropyl na methyl otu n'ime ọkpụkpụ azụ cellulose. Ihe si na HPMC polymer na-enye ihe pụrụ iche dị ka ịgbakọ, njide, imepụta ihe nkiri, na njide mmiri. Ka anyị banye n'ime usoro mmepụta HPMC zuru ezu.
1. Ị nweta akụrụngwa akụrụngwa:
Akụrụngwa bụ isi maka mmepụta HPMC bụ cellulose, nke sitere na isi mmalite ndị sitere na osisi dịka pulp osisi, akwa owu, ma ọ bụ osisi fibrous ndị ọzọ. A na-ahọrọ isi mmalite ndị a dabere na ihe ndị dị ka ịdị ọcha, ọdịnaya cellulose, na nkwado.
2. Mwepụta cellulose:
A na-ewepụta cellulose site na isi mmalite nke osisi a họọrọ site na usoro nhazi na usoro kemịkal. Na mbụ, a na-edozi ngwa ngwa ahụ, nke nwere ike ịgụnye ịsa ahụ, ihicha, na ihicha iji wepụ adịghị ọcha na mmiri. Mgbe ahụ, a na-ejikarị kemịkalụ dị ka alkalis ma ọ bụ acid agwọ cellulose ahụ iji mebie lignin na hemicellulose, na-ahapụ n'azụ eriri cellulose dị ọcha.
3. Etherification:
Etherification bụ usoro kemịkalụ bụ isi na mmepụta HPMC, ebe a na-ewebata otu hydroxypropyl na methyl n'ime ọkpụkpụ azụ cellulose. Nzọụkwụ a dị oké mkpa maka imegharị ihe onwunwe nke cellulose iji nweta ọrụ achọrọ nke HPMC. Etherification na-emekarị site na mmeghachi omume nke cellulose na propylene oxide (maka hydroxypropyl otu) na methyl chloride (maka methyl otu) na ọnụnọ alkali catalysts n'okpuru achịkwa ọnọdụ okpomọkụ na nrụgide.
4. Nnọpụiche na ịsa:
Mgbe etherification gasịrị, a na-ewepụ ngwakọta mmeghachi omume iji wepụ ihe ọ bụla alkali catalysts fọdụrụnụ ma mezie ọkwa pH. A na-emekarị nke a site n'ịgbakwunye acid ma ọ bụ isi dabere na ọnọdụ mmeghachi omume kpọmkwem. A na-esochi ịnọpụ iche site na ịsacha nke ọma iji wepụ ngwaahịa ndị sitere na ngwaahịa, kemịkalụ anaghị arụ ọrụ, na adịghị ọcha na ngwaahịa HPMC.
5. Nchacha na ihicha:
Ihe ngwọta HPMC nke neutralized na saa ya na-enweta nzacha iji kewapụ ihe siri ike ma nweta ngwọta doro anya. Nzacha nwere ike ịgụnye ụzọ dị iche iche dị ka vacuum filtration ma ọ bụ centrifugation. Ozugbo edozichara ngwọta ahụ, a na-akpọnwụ iji wepụ mmiri ma nweta HPMC n'ụdị ntụ ntụ. Ụzọ ihicha nwere ike ịgụnye ihicha ịgba, ihicha akwa mmiri, ma ọ bụ ihicha drum, dabere na nha urughuru chọrọ yana njirimara nke ngwaahịa ikpeazụ.
6. Egweri na sieve (Nhọrọ):
N'ọnọdụ ụfọdụ, na akpọnwụ HPMC ntụ ntụ nwere ike na-enweta n'ihu nhazi dị ka egweri na sieving iji nweta kpọmkwem urughuru nha ma melite flowability. Nzọụkwụ a na-enyere aka inweta HPMC nwere àgwà anụ ahụ na-agbanwe agbanwe dabara adaba maka ngwa dị iche iche.
7. Njikwa ogo:
N'ime usoro mmepụta ihe, a na-emejuputa usoro njikwa mma siri ike iji hụ na ịdị ọcha, nkwụsi ike, na arụmọrụ nke ngwaahịa HPMC. Usoro njikwa ogo nwere ike ịgụnye viscosity, nkesa nha nha, ọdịnaya mmiri, ogo nnọchi (DS), na akụrụngwa ndị ọzọ dị mkpa. A na-ejikarị usoro nyocha dị ka nha viscosity, spectroscopy, chromatography, na microscopy maka ntule dị mma.
8. Nkwakọ ngwaahịa na Nchekwa:
Ozugbo ngwaahịa HPMC gafere ule njikwa mma, a na-etinye ya n'ime arịa dabara adaba dị ka akpa ma ọ bụ drọm ma kpọọ ya dịka nkọwapụta. Nkwakọ ngwaahịa kwesịrị ekwesị na-enyere aka ichekwa HPMC pụọ na mmiri mmiri, mmetọ na mmebi anụ ahụ n'oge nchekwa na njem. A na-echekwa HPMC ngwugwu na ọnọdụ a na-achịkwa iji kwado nkwụsi ike ya na ndụ nchekwa ruo mgbe ọ dị njikere maka nkesa na iji ya.
Ngwa nke HPMC:
Hydroxypropyl Methylcellulose na-achọta ọtụtụ ojiji na ụlọ ọrụ dị iche iche gụnyere ọgwụ, ihe owuwu, nri, ihe ịchọ mma, na ngwaahịa nlekọta onwe onye. N'ọgwụ ọgwụ, a na-eji ya dị ka ihe nchikota, nke na-agbasasị, ihe nkiri mbụ na onye na-ewepụta ihe n'ụdị mbadamba. N'ihe owuwu, a na-eji HPMC n'ọrụ dị ka onye na-agbapụta mmiri, onye na-ejigide mmiri, yana ihe ngbanwe n'ụrọ nke simenti, plasta, na nrapado tile. N'ime nri, ọ na-arụ ọrụ dị ka ihe na-eku, stabilizer, na emulsifier na ngwaahịa dị ka sauces, ofe, na desserts. Na mgbakwunye, a na-eji HPMC eme ihe na ihe ịchọ mma na ngwaahịa nlekọta onwe onye maka imepụta ihe nkiri, ime mmiri na ihe na-emezi ederede.
Ihe gbasara gburugburu:
Mmepụta nke HPMC, dị ka ọtụtụ usoro mmepụta ihe, nwere mmetụta gburugburu ebe obibi. A na-agba mbọ iji kwalite nkwado nke mmepụta HPMC site na atumatu dị ka iji isi mmalite ume ọhụrụ, na-ebuli ojiji akụrụngwa, ibelata mmepụta ihe mkpofu, na itinye teknụzụ mmepụta gburugburu ebe obibi. Na mgbakwunye, mmepe nke HPMC dabere na bio nke ewepụtara site na isi mmalite dị ka algae ma ọ bụ gbaa ụka microbial na-egosi nkwa na ibelata akara ukwu gburugburu nke mmepụta HPMC.
mmepụta nke Hydroxypropyl Methylcellulose gụnyere usoro usoro nke na-amalite site na mmịpụta cellulose na mgbanwe kemịkalụ, ịdị ọcha, na njikwa mma. Ihe si na HPMC polymer na-enye ọrụ dị iche iche ma chọta ngwa na ụlọ ọrụ dị iche iche. Mgbalị maka nkwado nkwado na ọrụ gburugburu ebe obibi na-ebute ihe ọhụrụ na mmepụta HPMC, na-achọ ibelata mmetụta gburugburu ebe obibi ya ka ọ na-egbo mkpa na-eto eto maka polymer a vasatail.
Oge nzipu: Mar-05-2024