Hydroxypropyl methylcellulose (HPMC) bụ polymer vasatail na ọtụtụ ebe na-arụ ọrụ dị iche iche, mara maka pụrụ iche Njirimara na ngwa. Ngwakọta a bụ ihe sitere na cellulose, polymer eke dị na mgbidi cell osisi. Iji ghọta ihe mejupụtara hydroxypropylmethylcellulose, ọ dị mkpa ịbanye n'ime nhazi na njikọ nke mmepụta cellulose a.
Ọdịdị nke cellulose:
Cellulose bụ carbohydrate dị mgbagwoju anya nke nwere eriri ahịrị nke β-D-glucose nkeji jikọtara ya na njikọ β-1,4-glycosidic. A na-ejikọta ụdọ glucose ndị a site na njikọ hydrogen iji mepụta usoro ahịrị siri ike. Cellulose bụ isi ihe nhazi nke mgbidi cell osisi, na-enye ike na ike siri ike na mkpụrụ ndụ ihe ọkụkụ.
Mwepụta nke Hydroxypropyl Methylcellulose:
A na-ejikọta Hydroxypropyl methylcellulose site n'ịgbanwe cellulose na kemịkal na iwebata hydroxypropyl na methyl n'ime agbụ cellulose bụ isi. Mmepụta na-agụnyekarị usoro ndị a:
Mmeghachi omume etherification:
Methylation: Na-emeso cellulose na ngwọta alkaline na methyl chloride iji webata otu methyl (-CH3) n'ime ìgwè hydroxyl (-OH) nke cellulose.
Hydroxypropylation: Methylated cellulose na-emeghachi omume na propylene oxide iji webata otu hydroxypropyl (-CH2CHOHCH3) n'ime nhazi cellulose. Usoro a na-eme ka mmiri dị ike ma gbanwee ihe anụ ahụ nke cellulose.
ime ka ọ dị ọcha:
A na-asachapụ cellulose ahụ emezigharịrị ka ọ wepụ ihe ọ bụla reagents, ngwaahịa ma ọ bụ adịghị ọcha ọ bụla.
ihicha na egweri:
A na-akpọnwụ hydroxypropyl methylcellulose dị ọcha ma gbanye ya n'ime ntụ ntụ dị mma maka iji mee ihe n'ọtụtụ ngwa.
Ngwakọta nke Hydroxypropyl Methylcellulose:
Ihe mejupụtara hydroxypropyl methylcellulose bụ ogo nnọchi anya, nke na-ezo aka na ogo nke hydroxypropyl na methyl dị iche iche na-edochi otu hydroxyl na agbụ cellulose. Akara ule dị iche iche nke HPMC nwere ogo dị iche iche nke nnọchi, na-emetụta solubility ha, viscosity na ihe ndị ọzọ.
Enwere ike ịkọwa usoro kemịkalụ nke hydroxypropyl methylcellulose dị ka (C6H7O2 (OH) 3-mn (OCH3) m (OCH2CH (OH) CH3) n) _x, ebe m na n na-anọchi anya ogo nke nnọchi.
m: ogo methylation (otu methyl kwa otu glucose)
n: ogo nke hydroxypropylation (hydroxypropyl otu kwa glucose nkeji)
x: ọnụọgụ glucose dị na agbụ cellulose
Atụmatụ na ngwa:
Solubility: HPMC bụ mmiri-soluble, na ogo nke nnọchi na-emetụta ya solubility àgwà. Ọ na-emepụta ihe ngwọta doro anya na nke viscous na mmiri, na-eme ka ọ dị mma maka nhazi dị iche iche.
Viscosity: The viscosity nke HPMC ngwọta dabere na ihe ndị dị ka molekụla arọ na ogo nke nnọchi. Ngwongwo a dị oke mkpa maka ngwa dị ka ọgwụ na-achọ usoro ntọhapụ a na-achịkwa.
Nhazi ihe nkiri: HPMC nwere ike ịmepụta ihe nkiri dị gịrịgịrị ka ngwọta na-akpọnwụ, na-eme ka ọ baa uru na mkpuchi na ụlọ ọgwụ, nri na ụlọ ọrụ ndị ọzọ.
Stabilizers and Thickers: N'ime ụlọ ọrụ nri, a na-eji HPMC eme ihe dị ka ihe na-eme ka ihe na-esikwu ike na nkwụsi ike n'ụdị ngwaahịa dị iche iche, gụnyere sauces, desserts, na ngwaahịa esi nri.
Ngwa ọgwụ: A na-eji HPMC eme ihe n'ụdị usoro ọgwụ, gụnyere mbadamba, capsules, na ngwọta anya, n'ihi njirimara ntọhapụ ya na-achịkwa yana biocompatibility.
Ihe owuwu na mkpuchi: A na-eji HPMC eme ihe na-ewu ụlọ dịka ngwa agha, ihe nkpuchi tile na plasta. A na-ejikwa ya dị ka ihe na-agba agba na stabilizer na agba na mkpuchi.
Ngwaahịa Nlekọta Onwe Onye: N'ime ihe ịchọ mma na ụlọ ọrụ nlekọta onwe onye, a na-ahụ HPMC na ngwaahịa dị ka ude, lotions na shampoos, ebe ọ na-enye udidi na nkwụsi ike.
A na-enweta Hydroxypropyl methylcellulose site na methylation na hydroxypropylation nke cellulose. Ọ bụ polymer nwere ọtụtụ ebumnuche nwere ọtụtụ ojiji. Ngwongwo ya pụrụ iche na-eme ka ọ baa uru na ụlọ ọrụ dịka ọgwụ, nri, ihe owuwu na nlekọta onwe onye. Mgbanwe a na-achịkwa nke cellulose nwere ike imeziwanye njirimara nke HPMC, na-eme ka ọ bụrụ akụkụ dị mkpa nke ọtụtụ ngwaahịa anyị na-ezute na ndụ anyị kwa ụbọchị.
Oge nzipu: Jan-10-2024