HPMC bụ hydrophobic ma ọ bụ hydrophilic?

Hydroxypropyl methylcellulose (HPMC) bụ polymer vasatail nwere ma hydrophobic na hydrophilic Njirimara, na-eme ka ọ pụrụ iche n'ụdị dị iche iche nke ngwa n'ofe dị iche iche ọrụ. Iji ghọta hydrophobicity na hydrophilicity nke HPMC, anyị kwesịrị ịmụ usoro ya, ihe onwunwe na ngwa ya na omimi.

Ọdịdị nke hydroxypropyl methylcellulose:

HPMC bụ ihe sitere na cellulose, polymer eke dị na mgbidi cell osisi. Mgbanwe nke cellulose gụnyere iwebata hydroxypropyl na methyl n'ime ọkpụkpụ azụ cellulose. Mgbanwe a na-agbanwe ihe onwunwe nke polymer, na-enye ihe ndị a kapịrị ọnụ nke bara uru maka ọtụtụ ngwa.

Hydrophilicity nke HPMC:

Hydroxy:

HPMC nwere otu hydroxypropyl ma bụrụ hydrophilic. Ndị otu hydroxyl ndị a nwere mmekọrịta dị elu maka ụmụ irighiri mmiri n'ihi njikọta hydrogen.

Otu Hydroxypropyl nwere ike ịmepụta njikọ hydrogen na ụmụ irighiri mmiri, na-eme ka HPMC soluble n'ime mmiri ruo n'ókè ụfọdụ.

methyl:

Ọ bụ ezie na otu methyl na-enye aka na mkpokọta hydrophobicity nke molecule ahụ, ọ naghị emegide hydrophilicity nke otu hydroxypropyl.

Otu methyl bụ nke na-abụghị polar, ma ọnụnọ nke hydroxypropyl otu na-ekpebi àgwà hydrophilic.

Hydrophobicity nke HPMC:

methyl:

Otu methyl dị na HPMC na-ekpebi n'ókè ụfọdụ hydrophobicity ya.

Ọ bụ ezie na ọ bụghị dị ka hydrophobic dị ka ụfọdụ polymer synthetic zuru ezu, ọnụnọ nke otu methyl na-ebelata mkpokọta hydrophilicity nke HPMC.

Njirimara mmepụta ihe nkiri:

A maara HPMC maka ihe na-emepụta ihe nkiri na a na-ejikarị ya eme ihe na ọgwụ na ngwa ịchọ mma. Hydrophobicity na-enyere aka ịmepụta ihe nkiri nchebe.

Mmekọrịta ya na ihe ndị na-abụghị polar:

N'ime ngwa ụfọdụ, HPMC nwere ike imekọrịta ihe na ihe ndị na-abụghị polar n'ihi akụkụ hydrophobicity ya. Ngwongwo a dị oke mkpa maka usoro nnyefe ọgwụ na ụlọ ọrụ ọgwụ.

Ngwa nke HPMC:

ọgwụ:

A na-eji HPMC eme ihe n'ụdị usoro ọgwụ dịka ihe nchikota, ihe nkiri mbụ, na mgbanwe viscosity. Ikike imepụta ihe nkiri ya na-eme ka mwepụta ọgwụ na-achịkwa nke ọma.

A na-eji ya n'ụdị usoro onunu siri ike dịka mbadamba na capsules.

Ụlọ ọrụ ihe owuwu:

N'ebe a na-ewu ihe owuwu, a na-eji HPMC na ngwaahịa simenti na-eme ka ọrụ dị mma, njide mmiri na nrapado.

Hydrophilicity na-enyere aka idobe mmiri, ebe hydrophobicity na-enyere aka melite adhesion.

ụlọ ọrụ nri:

A na-eji HPMC eme ihe dị ka onye na-eme ihe na-esi ísì ụtọ na gelling na ụlọ ọrụ nri. Ọdịdị hydrophilic ya na-enyere aka ịmepụta gels kwụsiri ike ma na-achịkwa viscosity nke ngwaahịa nri.

ịchọ mma:

N'ụdị ihe ịchọ mma, a na-eji HPMC eme ihe na ngwaahịa dị ka ude na lotions n'ihi imepụta ihe nkiri na ihe na-eme ka ọ dị arọ.

Hydrophilicity na-eme ka hydration dị mma nke akpụkpọ ahụ.

na ngwụcha:

HPMC bụ polymer nke bụ ma hydrophilic na hydrophobic. Nhazi dị n'etiti hydroxypropyl na methyl dị iche iche na nhazi ya na-enye ya mgbanwe pụrụ iche, na-enye ya ohere ịnweta ngwa dịgasị iche iche. Ịghọta ihe ndị a dị oke mkpa iji kwado HPMC ka ọ bụrụ ihe eji eme ihe na ụlọ ọrụ dị iche iche, ebe a na-eji ike HPMC na-emekọrịta ihe na mmiri na ihe ndị na-abụghị polar maka ebumnuche dị iche iche.