Hydroxypropylmethylcellulose (HPMC) bụ mgbanwe sịntetik nke cellulose, polymer eke dị na mgbidi cell osisi. Ọ bụ ezie na HPMC n'onwe ya abụghị ihe biopolymer n'onwe ya ebe ọ bụ na a na-emepụta ya na kemịkalụ, a na-ewerekarị ya dị ka ọkara sịntetik ma ọ bụ gbanwetụrụ biopolymers.
A. Okwu mmalite nke hydroxypropyl methylcellulose:
Hydroxypropyl methylcellulose (HPMC):
Hydroxypropylmethylcellulose (HPMC) bụ ihe sitere na cellulose, polymer linear nke mejupụtara nkeji glucose. Cellulose bụ isi ihe nhazi nke mgbidi cell osisi. A na-eme HPMC site n'ịgbanwe cellulose na kemịkal site n'ịgbakwụnye hydroxypropyl na otu methyl.
B. Ọdịdị na arụmọrụ:
1.Chemical Ọdịdị:
Usoro kemịkalụ nke HPMC nwere akụkụ ọkpụkpụ azụ cellulose nwere hydroxypropyl na otu methyl. Ogo nnọchi anya (DS) na-ezo aka na nkezi ọnụọgụ hydroxypropyl na methyl otu glucose n'ime agbụ cellulose. Mgbanwe a na-agbanwe njirimara anụ ahụ na kemịkal nke cellulose, na-ebute ọtụtụ akara ule HPMC nwere viscosities dị iche iche, solubility na gel Njirimara.
2. Njirimara anụ ahụ:
Solubility: HPMC na-agbaze na mmiri ma mepụta ngwọta doro anya, na-eme ka ọ bụrụ ihe bara uru na ngwa dị iche iche gụnyere ọgwụ, nri, na ihe owuwu.
Viscosity: Enwere ike ịchịkwa viscosity nke ngwọta HPMC site n'ịgbanwe ogo nke nnọchi na ịdị arọ molecular nke polymer. Ngwongwo a dị oke mkpa maka ngwa dịka nhazi ọgwụ na ihe owuwu.
3. Ọrụ:
Thickeners: A na-ejikarị HPMC eme ihe dị ka ihe na-esi ísì ụtọ na nri, ọgwụ na ngwaahịa nlekọta onwe onye.
Ịmepụta ihe nkiri: Ọ nwere ike ịmepụta ihe nkiri na enwere ike iji ya kpuchie mbadamba ọgwụ na capsules, yana maka imepụta ihe nkiri maka ngwa dị iche iche.
Njide mmiri: A maara HPMC maka njide mmiri ya, na-enyere aka melite arụmọrụ na hydration nke ihe owuwu ụlọ dị ka ngwaahịa simenti.
C. Ngwa nke HPMC:
1. Ọgwụ:
Mbadamba ụrọ: A na-eji HPMC rụpụta ihe mkpuchi mbadamba iji chịkwaa ntọhapụ ọgwụ ma melite nkwụsi ike.
Nnyefe ọgwụ ọnụ: Nkwekọrịta bioocompatibility na njikwa ntọhapụ nke HPMC na-eme ka ọ dabara maka sistemụ nnyefe ọnụ.
2.Ụlọ ọrụ mmepụta ihe:
Ngwa ngwa ngwa na ngwaahịa ciment: A na-eji HPMC eme ihe na-ewu ụlọ iji kwalite njide mmiri, ịrụ ọrụ na nrapado.
3. Ụlọ ọrụ nri:
Ndị na-eme ihe siri ike na ndị na-eme ka ọ kwụsie ike: A na-eji HPMC eme ihe dị ka ihe na-esikwu ike na ihe nkwụsi ike na nri iji melite udidi na nkwụsi ike.
4. Ngwaahịa nlekọta onwe onye:
Ngwa ịchọ mma: A na-etinye HPMC n'ime usoro ịchọ mma maka imepụta ihe nkiri na ihe na-eme ka ọ sie ike.
5. Agba na mkpuchi:
Ihe mkpuchi mmiri: N'ime ụlọ ọrụ mkpuchi, a na-eji HPMC mee ihe na nhazi mmiri iji meziwanye rheology ma gbochie nhazi pigmenti.
6. Ihe gbasara gburugburu ebe obibi:
Ọ bụ ezie na HPMC n'onwe ya abụghị polymer zuru oke nke nwere ike imebi ndụ, mmalite cellulosic ya na-eme ka ọ dịtụ enyi na gburugburu ebe obibi ma e jiri ya tụnyere polymer synthetic zuru oke. HPMC nwere ike biodegrade n'okpuru ụfọdụ ọnọdụ, na ojiji ya na-adigide na biodegradable formulations bụ mpaghara nke na-aga n'ihu nyocha.
Hydroxypropylmethylcellulose (HPMC) bụ polymer semi-synthetic multifunctional ewepụtara na cellulose. Njirimara ya pụrụ iche na-eme ka ọ baa uru na ụlọ ọrụ dị iche iche gụnyere ọgwụ, ihe owuwu, nri, nlekọta onwe onye na agba. Ọ bụ ezie na ọ bụghị ụdị biopolymer kachasị dị ọcha, mmalite cellulose ya na ikike biodegradation kwekọrọ na ọchịchọ na-eto eto maka ihe ndị ọzọ na-adigide na ngwa dị iche iche. Nnyocha na-aga n'ihu na-aga n'ihu na-enyocha ụzọ iji kwalite ndakọrịta gburugburu ebe obibi nke HPMC ma gbasaa ojiji ya na usoro enyi na gburugburu ebe obibi.
Oge nzipu: Feb-07-2024