HydroxyPropyl Methylcellulose (HPMC)

HydroxyPropyl Methylcellulose (HPMC)

Hydroxypropyl Methylcellulose (HPMC), nke a makwaara dị ka hypromellose, bụ polymer vasatail ewepụtara na cellulose. A na-eji ya n'ọtụtụ ụlọ ọrụ dị iche iche maka ihe ndị pụrụ iche, gụnyere ọgwụ, ihe owuwu, nri, ihe ịchọ mma, na nlekọta onwe onye. N'ime ntuziaka a zuru oke, anyị ga-enyocha usoro kemịkalụ, akụrụngwa, usoro nrụpụta, ngwa na uru nke HPMC n'ụzọ zuru ezu.

1. Okwu mmalite nke HPMC:

Hydroxypropyl Methylcellulose (HPMC) bụ ether cellulose na-abụghị ionic nke sitere na cellulose eke sitere na mgbanwe kemịkalụ. A na-ejikọta ya site n'ịgwọ cellulose na propylene oxide na methyl chloride iji webata hydroxypropyl na methyl otu n'ime ọkpụkpụ cellulose. Ihe na-esi na polymer pụta na-egosiputa ihe dị iche iche nke na-eme ka ọ baa uru nke ukwuu na ngwa ụlọ ọrụ dị iche iche.

2. Ọdịdị kemịkalụ na Njirimara:

Ejiri usoro kemịkal ya mara HPMC, nke nwere ọkpụkpụ azụ cellulose nwere hydroxypropyl na methyl substituents jikọtara na otu hydroxyl. Ogo nke nnọchi (DS) nke otu hydroxypropyl na methyl nwere ike ịdịgasị iche, na-ebute akara ule dị iche iche nke HPMC nwere ihe dị iche iche dị ka viscosity, solubility, na gelation omume.

Ihe ndị dị ka ịdị arọ molekụla, ogo ngbanwe, na oke hydroxypropyl/methyl na-emetụta njirimara HPMC. Na mkpokọta, HPMC na-egosipụta njirimara ndị a:

  • Mmiri-slubility
  • Ikike imepụta ihe nkiri
  • Thicking na gelling Njirimara
  • Ọrụ elu
  • Nkwụsi ike n'elu oke pH
  • Ndakọrịta na ihe ndị ọzọ

3. Usoro nrụpụta:

Mmepụta nke HPMC gụnyere ọtụtụ usoro, gụnyere:

  1. Nkwadebe nke Cellulose: cellulose eke, nke a na-esikarị na pulp osisi ma ọ bụ owu, na-asachapụ ma nụchaa iji wepụ adịghị ọcha na lignin.
  2. Mmeghachi omume Etherification: A na-emeso cellulose na propylene oxide na methyl chloride na ọnụnọ alkali catalysts iji webata hydroxypropyl na methyl otu n'ime ọkpụkpụ cellulose.
  3. Nnọpụiche na ịsacha: A na-ewepụ ngwaahịa a na-esi na ya wepụ alkali na-agafe agafe wee saa ya iji wepụ ngwaahịa na adịghị ọcha.
  4. ihicha na egweri: HPMC dị ọcha na-akpọnwụ ma gbanye ya ka ọ bụrụ ntụ ntụ dị mma maka ngwa dị iche iche.

4. Ọkwa na nkọwapụta:

HPMC dị na ọkwa dị iche iche na nkọwapụta iji mezuo ihe achọrọ nke ụlọ ọrụ na ngwa dị iche iche. Ndị a na-agụnye mgbanwe dị na viscosity, nha urughuru, ogo nke nnọchi, na okpomọkụ gelation. Ọkwa HPMC nkịtị gụnyere:

  • Ogo viscosity ọkọlọtọ (dịka, 4000 cps, 6000 cps)
  • Ogo viscosity dị elu (dịka ọmụmaatụ, 15000 cps, 20000 cps)
  • Ogo viscosity dị ala (dịka ọmụmaatụ, 1000 cps, 2000 cps)
  • Ọkwa pụrụ iche maka ngwa ndị akọwapụtara (dịka ọmụmaatụ, ntọhapụ na-adịgide adịgide, ntọhapụ a na-achịkwa)

5. Ngwa nke HPMC:

HPMC na-ahụta ojiji a na-ejikarị na ụlọ ọrụ dị iche iche n'ihi ihe ndị dị na ya na ndakọrịta na ihe dị iche iche. Ụfọdụ n'ime isi ngwa nke HPMC gụnyere:

a. Ụlọ ọrụ ọgwụ:

  • Mbadamba ụrọ na capsule mkpuchi
  • Usoro ntọhapụ achịkwara
  • Njide na disintegrants na mbadamba
  • Ngwọta anya na nkwusioru
  • Usoro ndị dị n'elu dị ka ude na ointments

b. Ụlọ ọrụ ihe owuwu:

  • Ngwaahịa sitere na ciment na gypsum (dịka ọmụmaatụ, ngwa agha, plasta)
  • Tile adhesives na grouts
  • Sistemụ mkpuchi na imecha (EIFS)
  • Ngwakọta na-edozi onwe ya
  • Agba na mkpuchi mmiri

c. Ụlọ ọrụ nri:

  • Ihe na-eme ka ahụ sie ike na ngwaahịa nri
  • Emulsifier na onye nkwusioru na nri na akwa akwa
  • Ihe mgbakwunye eriri nri
  • Ime achịcha na ihe oriri na-enweghị Gluten

d. Nlekọta onwe onye na ihe ịchọ mma:

  • Thickerer na onye nkwusioru na lotions na ude
  • Ihe nkpuchi na ihe nkiri na-emebu na ngwaahịa nlekọta ntutu isi
  • Ntọhapụ a na-achịkwa na usoro nlekọta anụ ahụ
  • Anya tụlee na kọntaktị lens ngwọta

6. Uru nke Iji HPMC:

Iji HPMC na-enye ọtụtụ uru n'ofe ụlọ ọrụ dị iche iche:

  • Ịrụ ọrụ na ịdị mma ngwaahịa emelitere
  • Mgbanwe nhazi na nkwụsi ike
  • Ogologo ndụ agbatịla ma belata mmebi
  • Emelitere usoro arụmọrụ na ọnụ ahịa ọnụ ahịa
  • Nrube isi n'usoro iwu chọrọ yana ụkpụrụ nchekwa
  • Enyi na gburugburu ebe obibi na ihe dakọtara

7. Ọdịnihu na Ọdịnihu:

A na-atụ anya na ọchichọ HPMC ga-aga n'ihu na-eto eto, na-ebute site na ihe ndị dị ka ịba ụba obodo, mmepe akụrụngwa, na ịchọ ngwaahịa ọgwụ na nlekọta onwe onye. Mgbalị nyocha na mmepe na-aga n'ihu na-elekwasị anya n'ịkwalite usoro HPMC, ịgbasa ngwa ya, na imeziwanye usoro nrụpụta iji gboo mkpa ahịa ahịa.

8. Nkwubi okwu:

Hydroxypropyl Methylcellulose (HPMC) bụ polymer vasatail nwere ngwa dị iche iche n'ofe ọtụtụ ụlọ ọrụ. Ngwongwo ya pụrụ iche, dị ka mmiri solubility, ikike imepụta ihe nkiri, na ihe na-eme ka ọ dị arọ, na-eme ka ọ baa uru nke ukwuu na ọgwụ, ihe owuwu, nri, nlekọta onwe onye, ​​na ihe ịchọ mma. Ka teknụzụ na-aga n'ihu na ihe ndị ahịa chọrọ, a na-atụ anya na HPMC ga-arụ ọrụ dị mkpa n'ịkpụzi ọdịnihu nke ụlọ ọrụ dị iche iche.

Oge nzipu: Feb-11-2024