Hydroxypropyl Methylcellulose

Hydroxypropyl Methylcellulose

HydroxypropylMethylcellulose (HPMC) ma ọ bụ hypromellosebụ ihe ewepụtaras nke methyl cellulose ethers. Ọ bụfibrous na-acha ọcha ma ọ bụ na-acha ọcha ma ọ bụ granularcellulose etherntụ ntụ. Ugbu a ọ bụ cellulose ethers na arụmọrụ kachasị mma n'ụwa, na-ejikọta ndim, nkwụsịtụ, ịgbasa, emulsifying na stabilizing. Hydroxypropyl methyl cellulose (HPMC) adịghị egbu egbu, ọ dị mfe iji, ọ dịkwa mfe sorime na mmiri. Ọ bụ polyanion na ngwọta mmiri ma nwee ihe anụ ahụ pụrụ iche. The kpọmkwem arụmọrụ bụ dị n'okpuru:

 

Nkọwapụta anụ ahụ na kemịkalụ

Nkọwapụta

HPMC60E( 2910) HPMC65F( 2906) HPMC75K( 2208)
Gel okpomọkụ (℃) 58-64 62-68 70-90
Methoxy (WT%) 28.0-30.0 27.0-30.0 19.0-24.0
Hydroxypropoxy (WT%) 7.0-12.0 4.0-7.5 4.0-12.0
Viscosity (cps, 2% Ngwọta) 3, 5, 6, 15, 50,100, 400,4000, 10000, 40000, 60000,100000,150000,200000

 

Ihe owuwu ụlọ HPMC

 

Ihe owuwu Gnke HPMC Viscosity (NDJ, mPa.s, 2%) Viscosity (Brookfield, mPa.s, 2%)
HPMCMP400 320-480 320-480
HPMCMP60M 48000-72000 24000-36000
HPMCMP100M 80000-120000 40000-55000
HPMCMP150M 120000-180000 55000-65000
HPMCMP200M 180000-240000 70000-80000

 

Ọkwa nchacha HPMC

Ngwa nchaGnke HPMC Viscosity (NDJ, mPa.s, 2%) Viscosity (Brookfield, mPa.s, 2%)
HPMCMP100MS 80000-120000 40000-55000
HPMCMP150MS 120000-180000 55000-65000
HPMCMP200MS 180000-240000 70000-80000

 

 

Ceramic ọkwa HPMC

Ceramic Gnke HPMC Viscosity (NDJ, mPa.s, 2%) Viscosity (Brookfield, mPa.s, 2%)
HPMCMP4M 3200-4800 3200-4800
HPMCMP6M 4800-7200 4800-7200
HPMCMP10M 8000-12000 8000-12000

 

Ọkwa ịchọ mma HPMC

ịchọ mma Gnke HPMC Viscosity (NDJ, mPa.s, 2%) Viscosity (Brookfield, mPa.s, 2%)
HPMCMP60MS 48000-72000 24000-36000
HPMCMP100MS 80000-120000 40000-55000
HPMCMP200MS 160000-240000 70000-80000

 

Pharmaceutical ọkwa HPMC

Pharmaceutical ọkwa HPMC Viscosity (cps) kwuo
HPMC60E5 (E5) 4.0-6.0 HPMCHypromellose 2910
HPMC60E6 (E6) 4.8-7.2
HPMC60E15 (E15) 12.0-18.0
HPMC60E4000 (E4M) 3200-4800
HPMC65F50 (F50) 40-60 HPMCHypromellose 2906
HPMC75K100 (K100) 80-120 HPMCHypromellose 2208
HPMC75K4000 (K4M) 3200-4800
HPMC75K100000 (K100M) 80000-120000

 

PVC ọkwa HPMC

PVC HPMC ọkwa Viscosity (cps) kwuo
HPMC60E50(E50) 40-60 HPMC
HPMC65F50 (F50) 40-60 HPMC
HPMC75K100 (K100) 80-120 HPMC

 

 

Nri nri HPMC

Nri HPMC ọkwa Viscosity (cps) kwuo
HPMC60E5 (E5) 4.0-6.0 HPMC E464
HPMC60E15 (E15) 12.0-18.0
HPMC65F50 (F50) 40-60 HPMC E464
HPMC75K100000 (K100M) 80000-120000 HPMC E464
MC 55A30000 (MX0209) 24000-36000 MethylcelluloseE461

 

Atụmatụ:

1. Solubility: Ọ fọrọ nke nta ka ọ bụrụ ihe na-adịghị ike na ethanol zuru oke, ether na acetone, na-agbaze n'ime ngwọta colloidal doro anya ma ọ bụ ubé turbid na mmiri oyi. Enwere ike ịgbaze ya na ụfọdụ ihe mgbaze na-edozi ahụ, a pụkwara ịgbaze ya na ihe mgbaze nke mmiri na-edozi ahụ.

2. Nguzogide nnu: Ọ na-akwụsi ike na ngwọta mmiri mgbe salts metal ma ọ bụ organic electrolytes dị.

3. Ọrụ elu: enwere ike iji ya dị ka ihe nchebe colloid, emulsifier na dispersant.

4. PH-nkwụsi ike: PH uru dịtụ kwụsiri ike na nso nke 3.0 ~ 11.0. Acid ma ọ bụ alkali adịghị emetụta viscosity nke ngwọta mmiri.

Usoro ihe omimi:

C6H7O2(OH)3-mn(OCH3)m(OCH2CH(OH)CH3)n]x

Usoro nhazi nke molecular:

 

Na-eji nke HPMC:

Hydroxypropyl methylcellulose(HPMC) Enwere ike iji ya dị ka onye na-agba agba, onye na-ekesa, emulsifier, na onye na-emepụta ihe nkiri, wdg.Ihe owuwuỌkwa HPMC enwere ike iji ngwaahịa na kemịkalụ kwa ụbọchị, ngwa elektrọn, resins sịntetik, ihe owuwu na mkpuchi, ọkwa ọgwụ HPMC enwere ike iji namkpuchi mbadamba, wdg, na ọkwa nri HPMC enwere ike iji dị ka ihe mgbakwunye nri dị iche iche.

 

Ntuziaka HPMCNtuziaka:

1. Usoro mmiri ọkụ: Tinye 1/3 ma ọ bụ 2/3 nke mmiri n'ime akpa ahụ ma kpoo ya n'elu 80. Mbụ hydroxypropyl methyl cellulose(HPMC) nwere ike gbasasịa n'otu n'otu na mmiri ọkụ, wee gbakwunye ego mmiri oyi fọdụrụ na mmiri ọkụ na-ekpo ọkụ, dị jụụ mgbe ọ kpalitere.

2. Usoro ngwakọta ntụ ntụ: mix hydroxypropyl methyl cellulose(HPMC) ntụ ntụ na nnukwu ego nke ntụ ntụ ndị ọzọ, fesaa ya nke ọma site na ịgwakọta nkụ, wee tinye mmiri ka ọ gbazee ya..

3. Organic mgbaze wetting usoro: mbụ achụsasịa ma ọ bụ mmiri na hydroxypropyl methyl cellulose (HPMC) na ihe mgbaze organic, wee tinye mmiri ka ọ gbazee ya.

 

Nchekwa:

kaa akara ke jụụ na nkụ.

Ndụ nchekwa:

afọ atọ

Nkwakọ ngwaahịa:

25Kgs akwụkwọ akpa ma ọ bụeriri drum


Oge nzipu: Jan-01-2024