Hydroxypropyl Methylcellulose
HydroxypropylMethylcellulose (HPMC) ma ọ bụ hypromellosebụ ihe ewepụtaras nke methyl cellulose ethers. Ọ bụfibrous na-acha ọcha ma ọ bụ na-acha ọcha ma ọ bụ granularcellulose etherntụ ntụ. Ugbu a ọ bụ cellulose ethers na arụmọrụ kachasị mma n'ụwa, na-ejikọta ndim, nkwụsịtụ, ịgbasa, emulsifying na stabilizing. Hydroxypropyl methyl cellulose (HPMC) adịghị egbu egbu, ọ dị mfe iji, ọ dịkwa mfe sorime na mmiri. Ọ bụ polyanion na ngwọta mmiri ma nwee ihe anụ ahụ pụrụ iche. The kpọmkwem arụmọrụ bụ dị n'okpuru:
Nkọwapụta anụ ahụ na kemịkalụ
Nkọwapụta | HPMC60E( 2910) | HPMC65F( 2906) | HPMC75K( 2208) |
Gel okpomọkụ (℃) | 58-64 | 62-68 | 70-90 |
Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
Viscosity (cps, 2% Ngwọta) | 3, 5, 6, 15, 50,100, 400,4000, 10000, 40000, 60000,100000,150000,200000 |
Ihe owuwu ụlọ HPMC
Ihe owuwu Gnke HPMC | Viscosity (NDJ, mPa.s, 2%) | Viscosity (Brookfield, mPa.s, 2%) |
HPMCMP400 | 320-480 | 320-480 |
HPMCMP60M | 48000-72000 | 24000-36000 |
HPMCMP100M | 80000-120000 | 40000-55000 |
HPMCMP150M | 120000-180000 | 55000-65000 |
HPMCMP200M | 180000-240000 | 70000-80000 |
Ọkwa nchacha HPMC
Ngwa nchaGnke HPMC | Viscosity (NDJ, mPa.s, 2%) | Viscosity (Brookfield, mPa.s, 2%) |
HPMCMP100MS | 80000-120000 | 40000-55000 |
HPMCMP150MS | 120000-180000 | 55000-65000 |
HPMCMP200MS | 180000-240000 | 70000-80000 |
Ceramic ọkwa HPMC
Ceramic Gnke HPMC | Viscosity (NDJ, mPa.s, 2%) | Viscosity (Brookfield, mPa.s, 2%) |
HPMCMP4M | 3200-4800 | 3200-4800 |
HPMCMP6M | 4800-7200 | 4800-7200 |
HPMCMP10M | 8000-12000 | 8000-12000 |
Ọkwa ịchọ mma HPMC
ịchọ mma Gnke HPMC | Viscosity (NDJ, mPa.s, 2%) | Viscosity (Brookfield, mPa.s, 2%) |
HPMCMP60MS | 48000-72000 | 24000-36000 |
HPMCMP100MS | 80000-120000 | 40000-55000 |
HPMCMP200MS | 160000-240000 | 70000-80000 |
Pharmaceutical ọkwa HPMC
Pharmaceutical ọkwa HPMC | Viscosity (cps) | kwuo |
HPMC60E5 (E5) | 4.0-6.0 | HPMCHypromellose 2910 |
HPMC60E6 (E6) | 4.8-7.2 | |
HPMC60E15 (E15) | 12.0-18.0 | |
HPMC60E4000 (E4M) | 3200-4800 | |
HPMC65F50 (F50) | 40-60 | HPMCHypromellose 2906 |
HPMC75K100 (K100) | 80-120 | HPMCHypromellose 2208 |
HPMC75K4000 (K4M) | 3200-4800 | |
HPMC75K100000 (K100M) | 80000-120000 |
PVC ọkwa HPMC
PVC HPMC ọkwa | Viscosity (cps) | kwuo |
HPMC60E50(E50) | 40-60 | HPMC |
HPMC65F50 (F50) | 40-60 | HPMC |
HPMC75K100 (K100) | 80-120 | HPMC |
Nri nri HPMC
Nri HPMC ọkwa | Viscosity (cps) | kwuo |
HPMC60E5 (E5) | 4.0-6.0 | HPMC E464 |
HPMC60E15 (E15) | 12.0-18.0 | |
HPMC65F50 (F50) | 40-60 | HPMC E464 |
HPMC75K100000 (K100M) | 80000-120000 | HPMC E464 |
MC 55A30000 (MX0209) | 24000-36000 | MethylcelluloseE461 |
Atụmatụ:
1. Solubility: Ọ fọrọ nke nta ka ọ bụrụ ihe na-adịghị ike na ethanol zuru oke, ether na acetone, na-agbaze n'ime ngwọta colloidal doro anya ma ọ bụ ubé turbid na mmiri oyi. Enwere ike ịgbaze ya na ụfọdụ ihe mgbaze na-edozi ahụ, a pụkwara ịgbaze ya na ihe mgbaze nke mmiri na-edozi ahụ.
2. Nguzogide nnu: Ọ na-akwụsi ike na ngwọta mmiri mgbe salts metal ma ọ bụ organic electrolytes dị.
3. Ọrụ elu: enwere ike iji ya dị ka ihe nchebe colloid, emulsifier na dispersant.
4. PH-nkwụsi ike: PH uru dịtụ ike na nso nke 3.0 ~ 11.0. Acid ma ọ bụ alkali adịghị emetụta viscosity nke ngwọta mmiri.
Usoro ihe omimi:
〔C6H7O2(OH)3-mn(OCH3)m(OCH2CH(OH)CH3)n]x
Usoro nhazi nke molecular:
Na-eji nke HPMC:
Hydroxypropyl methylcellulose(HPMC) Enwere ike iji ya dị ka onye na-agba agba, onye na-ekesa, emulsifier, na onye na-emepụta ihe nkiri, wdg.Ihe owuwuỌkwa HPMC enwere ike iji ngwaahịa na kemịkalụ kwa ụbọchị, ngwa elektrọn, resins sịntetik, ihe owuwu na mkpuchi, ọkwa ọgwụ HPMC enwere ike iji namkpuchi mbadamba, wdg, na ọkwa nri HPMC enwere ike iji dị ka ihe mgbakwunye nri dị iche iche.
Ntuziaka HPMCNtuziaka:
1. Usoro mmiri ọkụ: Tinye 1/3 ma ọ bụ 2/3 nke mmiri n'ime akpa ahụ ma kpoo ya n'elu 80. Mbụ hydroxypropyl methyl cellulose(HPMC) nwere ike gbasasịa n'otu n'otu na mmiri ọkụ, wee gbakwunye ego mmiri oyi fọdụrụ na mmiri ọkụ na-ekpo ọkụ, dị jụụ mgbe ọ kpalitere.
2. Usoro ngwakọta ntụ ntụ: mix hydroxypropyl methyl cellulose(HPMC) ntụ ntụ na nnukwu ego nke ntụ ntụ ndị ọzọ, fesaa ya nke ọma site na ịgwakọta nkụ, wee tinye mmiri ka ọ gbazee ya..
3. Organic mgbaze wetting usoro: mbụ gbasasịa ma ọ bụ mmiri na hydroxypropyl methyl cellulose (HPMC) na ihe mgbaze organic, wee tinye mmiri ka ọ gbazee ya.
Nchekwa:
kaa akara na ebe dị jụụ na nkụ.
Ndụ nchekwa:
afọ atọ
Nkwakọ ngwaahịa:
25Kgs akwụkwọ akpa ma ọ bụeriri drum
Oge nzipu: Jan-01-2024