HPMC VS HEC: Ọdịiche 6 I Kwesịrị Ịma!

Ewebata:

Hydroxypropylmethylcellulose (HPMC) na hydroxyethylcellulose (HEC) bụ ihe mgbakwunye a na-ejikarị na nri, ịchọ mma na ụlọ ọrụ ọgwụ. Ihe ndị a na-emepụta cellulose nwere atụmanya ngwa sara mbara n'ihi ike mmiri ha pụrụ iche, nkwụsi ike siri ike, na ikike ịmepụta ihe nkiri dị mma.

1.Chemical Ọdịdị:

HPMC bụ polymer sịntetik nke sitere na cellulose. A na-eme ya site n'ịgbanwe cellulose eke ekemịkal site n'ịgbakwụnye propylene oxide na methyl chloride. HEC bụkwa ụdị mkpụrụ ndụ cellulose, mana a na-eme ya site n'imeghachi cellulose eke na ethylene oxide wee mesoo ya na alkali.

2. Solubility:

Ma HPMC na HEC bụ mmiri-soluble na ike agbaze na mmiri oyi. Ma solubility nke HEC dị ala karịa HPMC. Nke a pụtara HPMC nwere mma dispersibility na ike ga-eji ọzọ mfe na formulations.

3. Viscosity:

HPMC na HEC nwere njirimara viscosity dị iche iche n'ihi usoro kemịkalụ ha. HEC nwere ịdị arọ molekụla dị elu na usoro denser karịa HPMC, nke na-enye ya viscosity dị elu. Ya mere, HEC na-ejikarị dị ka a thickener na formulations chọrọ elu viscosity, mgbe HPMC na-eji na formulations chọrọ ala viscosity.

4. Ịrụ ihe nkiri:

Ma HPMC na HEC nwere ikike imepụta ihe nkiri mara mma. Mana HPMC nwere okpomọkụ na-emepụta ihe nkiri dị ala, nke pụtara na enwere ike iji ya na obere okpomọkụ. Nke a na-eme ka HPMC dabara adaba maka ojiji na usoro nke chọrọ oge ihicha ngwa ngwa yana nrapado ka mma.

5. Nkwụsi ike:

HPMC na HEC kwụsiri ike n'okpuru ọtụtụ pH na ọnọdụ okpomọkụ. Agbanyeghị, HEC na-enwe mmetụta maka mgbanwe pH karịa HPMC. Nke a pụtara na a ga-eji HEC mee ihe na usoro nwere pH nke 5 ruo 10, ebe HPMC nwere ike iji mee ihe na pH buru ibu.

6. Ngwa:

Ụdị dị iche iche nke HPMC na HEC na-eme ka ha dị mma maka ngwa dị iche iche. A na-ejikarị HEC eme ihe dị ka ihe na-eme ka ọ dị arọ na nhazi ihe ịchọ mma na ọgwụ. A na-ejikwa ya dị ka ihe nkedo na onye na-emepụta ihe nkiri na mbadamba mbadamba. A na-eji HPMC eme ihe dị ka ihe na-agbapụta, stabilizer, na onye na-emepụta ihe nkiri na nri, ọgwụ na ihe ịchọ mma. A na-ejikwa ya dị ka onye na-ahụ maka gelling na ụfọdụ ngwa nri.

Na ngwụcha:

HPMC na HEC bụ mkpụrụ ndụ cellulose nwere ihe pụrụ iche dabara adaba maka ngwa dị iche iche. Ịghọta ọdịiche dị n'etiti ihe mgbakwunye abụọ a nwere ike inyere gị aka ịhọrọ nke ziri ezi maka uzommeputa gị. N'ozuzu, HPMC na HEC bụ ihe mgbakwunye dị mma ma dị irè nke na-enye ọtụtụ uru na nri, ịchọ mma na ụlọ ọrụ ọgwụ.