HPMC maka ihe nkiri mkpuchi

A na-ejikarị hydroxylthyl methyl cellulose (Hpmc) a na-ejikarị ya na ụlọ ọrụ ọgwụ dị ka ihe na-adịghị mma na usoro ihe nkiri. Ibe ihe nkiri bụ usoro a dị mkpa, a na-etinye akwa polymer nke polymer na usoro onunu ogwu siri ike, dịka mbadamba ma ọ bụ capsules. HPMC na-enye uru dị iche iche na ngwa fim, gụnyere ihe nkiri, adhesion, na nchịkwa nlalaba wepụta. Nke a bụ nnyocha nke ngwa, ọrụ, na echiche nke HPMC na fim mkpuchi:

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1.1 na-arụ ọrụ na usoro ihe nkiri

A na-eji HPMC dị ka ndị na-eme ihe nkiri na-eme ihe nkiri na-emepụta ihe nkiri na-eme ọgwụ. Ọ na - enye mkpuchi dị mma na edo edo na elu nke ụdị onunu ogwu siri ike, na-enye aka mee ka ọdịdị ya, nkwụsi ike, ma belata ilo.

1.2 Uru na Ngwa mkpuchi mkpuchi

• Usoro ihe nkiri: HPMC na-etolite ihe nkiri na-agbanwe agbanwe na nke atụmanya mgbe etinyere ya n'elu mbadamba ma ọ bụ capsules, na-enye nchebe ma na-eme ka ihe dị mma na-eme ihe.
• Adhesion: HPMC na-eme ka ihe nkiri na-eme ka ihe nkiri na-agbasa uniformly na mkpụrụ na anaghị agbaji ma ọ bụ bee.
• Nchịkwa nke a na-achịkwa: Dabere na ọkwa dị iche iche eji, HPMC nwere ike itinye aka na mwepụta nke ihe na-arụ ọrụ (API) site na usoro onunu ogwu.

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2.1 ihe nkiri

HPMC na-arụ ọrụ dị ka onye na-eme ihe nkiri na-eme ihe nkiri, na-eke ihe nkiri dị mkpa na nke edobere n'elu mbadamba ma ọ bụ capsules. Ihe nkiri a na-enye nchedo, na-egosi uto ma ọ bụ isi nke ọgwụ, ma na-eme ka ọdịdị niile dị elu.

2.2 Adhesion

HPMC na - eme ka ndọlite ​​n'etiti ihe nkiri na mkpụrụ, na - ejide nkwụsi ike ma na - adịgide adịgide. Adhesion na-egbochi ihe ndị dị ka cracking ma ọ bụ peeling n'oge nchekwa ma ọ bụ njikwa.

2.3 na-achịkwa nchịkwa

Ezubere akara ugo nke Hpmc iji nye aka na ihe ndi ozo, na-emetụta ọnụego ntọhapụ nke ngwa ọrụ site na usoro onunu ogwu. Nke a dị mkpa iji wepụta ma ọ bụ na-akwado ya.

2.4 Nkwalite Mmalite

Ojiji nke HPMC na usoro ihe nkiri na-asọpụta nwere ike ime ka ọ na-ahụ anya na ụdị usoro onunu ogwu, na-eme ka ọ nabata karịa ndị ọrịa. Ihe nkiri ahụ na-eme ka ọ dị mma ma na-acha uhie uhie.

3. Ngwa na ihe nkiri

3.1 Mbadamba

A na-ejikarị HPMC a na-ejikarị mbadamba ihe nkiri, na-enye oyi akwa ma melite ọdịdị ha. Ọ dị mma maka usoro usoro dị iche iche mbadamba mbadamba, gụnyere ntọhapụ ngwa ngwa na nke gbatịpụrụ.

3,2 Capsules

Na mgbakwunye na mbadamba, a na-eji HPMC mee ihe maka ihe nkiri mkpuchi mkpuchi, na-enye aka na nkwụsi ike ha ma na-enye ọdịdị otu. Nke a dị ezigbo mkpa maka uto- ma ọ bụ usoro mmetụta isi.

3.3 Iri nri

Enwere ike iji HPMC rụọ ọrụ iji kpuchie uto ma ọ bụ isi nke ihe na-emepụta ọgwụ, na-eme ka ụmụaka na-anabata ọrịa ma ọ bụ usoro.

3.4 na-achịkwa ntọhapụ ntọhapụ

Maka idozigharị ma ọ bụ nke na-akwado ya, HPMC na-arụ ọrụ dị oke mkpa iji nweta profaịlụ a chọrọ, na-enye ohere maka ntọhapụ ọgwụ ndị ọzọ buru ibu ma na-achịkwa ya.

4. Ndị na-atụle ma na-akpachapụ anya

4.1 Nchọpụta Ntọala

Nhọrọ nke ọkwa HPMC kwesịrị ịdabere na ihe ndị akọwapụtara nke ngwa fim, gụnyere akụrụngwa ihe nkiri achọrọ, adhesion, na njirimara a na-achịkwa ya.

2.2 ndakọrịta

Ndaghachi omume na ihe ndị ọzọ na-arụ ọrụ na ihe na-emepụta ọgwụ dị mkpa iji hụ na nkwụsi ike na arụmọrụ nke mpempe akwụkwọ onunu ogwu.

4.3 ihe nkiri ihe nkiri

A ga-eji nlezianya na-achịkwa ihe nkiri a ga-eji nlezianya na-achịkwa ihe achọrọ na iji zere ịta ahụhụ, nke nwere ike imetụta mgbasa na bioaivaions.

5. Mmechi

Hydroxypylthylthylthylthyl cellulose bụ ihe dị oke mma na ngwa ọgwụ na-eme ọgwụ, na-enye usoro ịse, adhesion, na njikwa wepụta oge. Offdị dossion ụdị nke fim na-enye ọfụma, nchebe, yana ịnara onye ọrịa. Jiri nlezianya na-echebara nhọrọ ogo, ndakọrịta, na ọkpụrụkpụ ihe nkiri dị mkpa iji hụ na ngwa ihe na-aga nke ọma nke HPMC na usoro ihe nkiri dị iche iche.