Hydroxypropyl methylcellulose (HPMC) bụ polymer multifunctional nwere ngwa obosara na ụlọ ọrụ dị iche iche dị ka ọgwụ, ihe owuwu, nri, ihe ịchọ mma, wdg. Njirimara na ọrụ ya dị iche iche na-eme ka ọ bụrụ ihe bara uru n'ọtụtụ ngwaahịa. Nke a bụ nyocha dị omimi nke HPMC:
1. Njirimara HPMC:
Ọdịdị kemịkal: HPMC sitere na cellulose, polymer eke dị na osisi. A na-emepụta ya site n'ịgbanwe cellulose n'ụzọ kemịkal na propylene oxide na methyl chloride. Ogo nke nnọchi nke hydroxypropyl na otu methoxy na-ekpebi njirimara ya.
Solubility: HPMC na-agbaze na mmiri n'elu oke okpomọkụ. Solubility na-adabere n'ogo ngbanwe na ịdị arọ molekụla nke polymer. Ọkwa ngbanwe dị elu na-eduga n'ịba ụba mmiri solubility.
Viscosity: HPMC na-egosipụta pseudoplastic ma ọ bụ ịkpa àgwà dị nro, nke pụtara na viscosity ya na-ebelata n'okpuru nrụgide siri ike. Enwere ike idozi viscosity nke ngwọta HPMC site na ịhazigharị paramita dị ka ịdị arọ molekụla, ogo nke nnọchi, na itinye uche.
Nhazi ihe nkiri: HPMC na-etolite ihe nkiri doro anya ma na-agbanwe agbanwe mgbe a na-etinye ya na ngwọta. Enwere ike ịmegharị ihe nkiri ihe nkiri site n'ịgbanwe mkpokọta polymer na ọnụnọ nke plasticizers.
Nkwụsi ike nke okpomọkụ: HPMC nwere ezigbo nkwụsi ike nke okpomọkụ, yana okpomoku ire ere na-adịkarị karịa 200°C. Nke a na-eme ka ọ dị mma maka usoro nhazi dị iche iche, gụnyere ọkụ ọkụ na-ekpo ọkụ na ịkpụzi injection.
Hydrophilicity: N'ihi ọdịdị hydrophilic ya, HPMC nwere ike ịmịkọrọ ma jide nnukwu mmiri. Ngwongwo a bara uru na ngwa dị ka nnyefe ọgwụ na-achịkwa yana dị ka ihe na-eme ka ọ dị arọ na sistemu mmiri.
Ndakọrịta: HPMC dakọtara na ihe ndị ọzọ dị iche iche, gụnyere polymers ndị ọzọ, plasticizers, na ngwa ọgwụ na-arụ ọrụ (API). Ndakọrịta a na-enye ohere iji atụmatụ ahaziri ahazi usoro mgbagwoju anya.
Njirimara ndị na-abụghị ionic: HPMC bụ polymer na-abụghị ionic, nke pụtara na ọ naghị ebu ụgwọ eletrik ọ bụla. Ngwongwo a na-ebelata mmekọrịta ya na ụdị ebubo na nhazi ahụ ma kwalite nkwụsi ike ya na ngwọta.
2.HPMC ọrụ:
Binders: N'ụdị mbadamba mbadamba, HPMC na-arụ ọrụ dị ka ihe nkedo, na-akwalite adhesion n'etiti irighiri ihe na ịbawanye ike n'ibu nke mbadamba. Ọ na-enyekwara mbadamba nkume ndị ahụ aka igbasa ma e richara ya.
Ihe mkpuchi ihe nkiri: A na-ejikarị HPMC eme ihe dị ka ihe mkpuchi ihe nkiri maka mbadamba na capsules. Ọ na-etolite otu uwe, mkpuchi nchebe nke na-ekpuchi uto na isi nke ọgwụ ahụ, na-eme ka nkwụsi ike, na-eme ka ọ dị mfe ilo.
Ntọhapụ na-adịgide adịgide: Enwere ike iji HPMC jikwaa ọnụego ntọhapụ nke ọgwụ sitere na ụdị usoro onunu ogwu. Site na hydrating iji mepụta akwa gel, HPMC nwere ike igbu oge ntọhapụ ọgwụ ma nye mmetụta ọgwụgwọ na-adịgide adịgide.
Viscosity Modifier: Na sistemu mmiri, HPMC na-arụ ọrụ dị ka ihe ngbanwe viscosity ma ọ bụ thickener. Ọ na-enye omume ịgba ọsọ pseudoplastic, na-eme ka nkwụsi ike na arụmọrụ ngwa nke usoro dị ka ude, lotions na gels.
Ihe nkwusioru: A na-eji HPMC kwụsie ike nkwusioru nke irighiri irighiri ihe na usoro mmiri mmiri. Ọ na-egbochi edozi site n'ịbawanye viscosity nke na-aga n'ihu na-aga n'ihu na ime ka urughuru dispersion.
Emulsifier: Na emulsion formulations, HPMC stabilizes interface n'etiti mmanụ na mmiri n'ụzọ, na-egbochi oge nkewa na emulsification. Ọ na-eme ka nkwụsi ike na ndụ nchekwa nke lotions dị na ngwaahịa ndị dị ka ude, ointments na lotions.
Hydrogel Formation: HPMC nwere ike ịmepụta hydrogels mgbe mmiri gbara ya mmiri, na-eme ka ọ baa uru na mgbakwasa ọnya, anya anya anya, na usoro nnyefe ọgwụ. Hydrogels ndị a na-enye ebe mmiri mmiri maka ọgwụgwọ ọnya na enwere ike ibunye ọgwụ maka nnyefe mpaghara.
Ihe na-eme ka ọ dị arọ: A na-ejikarị HPMC eme ihe dị ka ihe na-eme ka ọ sie ike na ngwaahịa nri dị ka sauces, uwe na desserts. Ọ na-enye udidi dị nro ma na-eme ka uto na-agbanweghị ụtọ ma ọ bụ ọdịnaya nri.
Ihe mgbakwunye ihe owuwu: N'ụlọ ọrụ ihe owuwu, a na-eji HPMC dị ka ihe na-edobe mmiri n'ụrọ na plasta sitere na ciment. Ọ na-eme ka arụ ọrụ dịkwuo mma, adhesion, ma na-ebelata mgbawa site n'ibelata evaporation mmiri.
Mgbanwe elu: HPMC nwere ike gbanwee njirimara elu nke ihe ndị siri ike dị ka akwụkwọ, textiles na ceramics. Ọ na-eme ka mbipụta, nrapado na ihe mgbochi nke mkpuchi na ihe nkiri dịkwuo mma.
Hydroxypropylmethylcellulose (HPMC) bụ polymer vasatail nwere ihe dị iche iche na ọrụ. Solubility ya, viscosity, ikike imepụta ihe nkiri na ndakọrịta na-eme ka ọ bụrụ ihe dị mkpa n'ọtụtụ ngwa n'ofe ụlọ ọrụ. Site na ọgwụ na-ewu ụlọ, nri ruo ihe ịchọ mma, HPMC na-aga n'ihu na-arụ ọrụ dị mkpa n'ịkwalite arụmọrụ ngwaahịa na ịdị mma. Ka nyocha na teknụzụ na-aga n'ihu, ike na ike nke HPMC nwere ike gbasaa ọzọ, na-ebugharị ihe ọhụrụ n'ichepụta ihe na mmepe ngwaahịa.
Oge nzipu: Feb-23-2024