HPMC (hydroxypropyl methylcellulose)Capsules bụ otu n'ime ihe capsule ndị a na-ejikarị na ọgwụ ọgbara ọhụrụ na mgbakwunye nri. A na-eji ya n'ọtụtụ ebe na ụlọ ọrụ ọgwụ na ụlọ ọrụ nlekọta ahụike, ndị anaghị eri anụ na ndị ọrịa nwere allergies na-amasị ya n'ihi ihe ọkụkụ sitere na ya. Capsules HPMC na-eji nwayọọ nwayọọ na-agbaze n'ime eriri afọ eriri afọ mgbe ejiri ya, si otú ahụ na-ahapụ ihe ndị na-arụ ọrụ n'ime ha.
1. Nchịkọta nke HPMC capsule mgbasa oge
Oge mgbasa nke capsules HPMC na-adịkarị n'etiti nkeji 10 na 30, nke dabere na ọkpụrụkpụ mgbidi capsule, usoro nkwadebe, ọdịdị nke ọdịnaya capsule, na ihe gburugburu ebe obibi. E jiri ya tụnyere capsules gelatin ọdịnala, ọnụego mgbasa nke capsules HPMC na-adị ntakịrị nwayọ, mana ọ ka dị n'ime oke nnabata nke eriri afọ mmadụ. N'ozuzu, ọgwụ ma ọ bụ nri nwere ike ịwepụta ngwa ngwa na itinye uche ya mgbe agbazechara capsule, na-ahụ na bioavailability nke ihe ndị na-arụ ọrụ.
2. Ihe ndị na-emetụta ọnụego mgbasa nke HPMC capsules
pH uru na okpomọkụ
Capsules HPMC nwere mma solubility dị mma na gburugburu acidic na nnọpụiche, yabụ na ha nwere ike gbaze ngwa ngwa n'ime afọ. Uru pH nke afọ na-adịkarị n'etiti 1.5 na 3.5, na gburugburu acid a na-enyere aka ịgbasa capsules HPMC. N'otu oge ahụ, okpomoku nkịtị nke ahụ mmadụ (37 Celsius) nwere ike ịkwalite mgbaze ngwa ngwa nke capsules. Ya mere, na gburugburu acid nke afọ, HPMC capsules nwere ike ịgbari ngwa ngwa ma hapụ ọdịnaya ha.
HPMC capsule mgbidi ọkpụrụkpụ na njupụta
Ọkpụrụkpụ nke mgbidi capsule na-emetụta ozugbo oge mgbasa. Mgbidi capsule dị arọ na-ewe oge karịa ka ọ gbazee kpamkpam, ebe mgbidi capsule dị gịrịgịrị na-agbaze ngwa ngwa. Na mgbakwunye, njupụta nke capsule HPMC ga-emetụta ọnụego mgbasa ya. Capsules denser ga-ewe ogologo oge iji gbarie n'ime afọ.
Ụdị na ọdịdị nke ọdịnaya
Ihe ndị a na-etinye n'ime capsule nwekwara mmetụta ụfọdụ na ọnụego mgbasa. Dịka ọmụmaatụ, ọ bụrụ na ihe dị n'ime ya bụ acidic ma ọ bụ soluble, capsule ga-agbaze ngwa ngwa n'ime afọ; ebe maka ụfọdụ ihe na-ejupụta mmanụ, ọ nwere ike iwe ogologo oge iji gbasaa. Na mgbakwunye, ọnụego mgbasa nke ntụ ntụ na mmiri mmiri dịkwa iche iche. Nkesa nke mmiri mmiri dị n'ime ya bụ otu, nke na-eme ka mgbawa ngwa ngwa nke capsules HPMC.
Nha Capsule
HPMCcapsules dị iche iche nkọwa (dị ka No. 000, No. 00, No. 0, wdg) nwere dị iche iche mgbasa ọnụego. N'ikwu okwu n'ozuzu, obere capsules na-ewe oge dị mkpirikpi iji gbazee, ebe nnukwu capsules nwere mgbidi siri ike na ihe ndị ọzọ dị n'ime ya, ya mere ha na-ewe ntakịrị oge iji gbazee.
Usoro nkwadebe
N'oge usoro mmepụta nke capsules HPMC, ọ bụrụ na ejiri plasticizers ma ọ bụ tinye ihe ndị ọzọ, enwere ike ịgbanwe àgwà mgbasa nke capsules. Dịka ọmụmaatụ, ụfọdụ ndị na-emepụta ihe na-agbakwunye glycerin akwukwo nri ma ọ bụ ihe ndị ọzọ na HPMC iji mee ka ngbanwe nke capsules dịkwuo mma, nke nwere ike imetụta ọnụego nkwụsị nke capsules ruo n'ókè ụfọdụ.
Iru mmiri na ọnọdụ nchekwa
Capsules HPMC na-enwe mmetụta maka iru mmiri na ọnọdụ nchekwa. Ọ bụrụ na echekwara ya na ebe kpọrọ nkụ ma ọ bụ nke dị elu, capsules nwere ike ịghachị, si otú ahụ na-agbanwe ọnụego mgbasa n'ime afọ mmadụ. Ya mere, HPMC capsules na-emekarị mkpa ka echekwara na ala okpomọkụ na akọrọ gburugburu ebe obibi iji hụ na nkwụsi ike nke mgbasa ha ọnụego na àgwà.
3. Usoro mgbasa nke HPMC capsules
A na-ekewa usoro mgbasa nke capsules HPMC n'ime usoro atọ:
Ogbo mmịnye mmiri nke mbụ: Mgbe nrichara ya, capsules HPMC na-ebu ụzọ amịpụta mmiri site na ihe ọṅụṅụ afọ. N'elu capsule na-aghọ mmiri wee malite nwayọọ nwayọọ. Ebe ọ bụ na ihe owuwu nke capsules HPMC nwere ụfọdụ ogo nnabata mmiri, ọkwa a na-adịkarị ngwa ngwa.
Ọzịza na mgbakasị ahụ: Mgbe ọ gbasasịrị mmiri, mgbidi capsule ahụ na-eji nwayọọ nwayọọ zaa ka ọ ghọọ oyi akwa gelatin. Ihe oyi akwa a na-eme ka capsule ahụ gbasaa ọzọ, na-ekpughe ihe dị n'ime ya wee hapụ ya. Oge a na-ekpebi ogo mgbasa nke capsule ma bụrụkwa isi ihe na mwepụta ọgwụ ma ọ bụ nri.
Oge mgbasa ozi zuru oke: Ka mgbasa ahụ na-aga n'ihu, capsule na-agbaze kpamkpam, a na-ewepụta ihe dị n'ime ya nke ọma, ahụ mmadụ nwere ike ịbanye ya. Na-emekarị n'ime nkeji 10 ruo 30, HPMC capsules nwere ike mezue usoro site na nkwụsịtụ ruo nkwụsịtụ.
Usoro nkwadebe
N'oge usoro mmepụta nke capsules HPMC, ọ bụrụ na ejiri plasticizers ma ọ bụ tinye ihe ndị ọzọ, enwere ike ịgbanwe àgwà mgbasa nke capsules. Dịka ọmụmaatụ, ụfọdụ ndị na-emepụta ihe na-agbakwunye glycerin akwukwo nri ma ọ bụ ihe ndị ọzọ na HPMC iji mee ka ngbanwe nke capsules dịkwuo mma, nke nwere ike imetụta ọnụego nkwụsị nke capsules ruo n'ókè ụfọdụ.
Iru mmiri na ọnọdụ nchekwa
Capsules HPMC na-enwe mmetụta maka iru mmiri na ọnọdụ nchekwa. Ọ bụrụ na echekwara ya na ebe kpọrọ nkụ ma ọ bụ nke dị elu, capsules nwere ike ịghachị, si otú ahụ na-agbanwe ọnụego mgbasa n'ime afọ mmadụ. Ya mere, HPMC capsules na-emekarị mkpa ka echekwara na ala okpomọkụ na akọrọ gburugburu ebe obibi iji hụ na nkwụsi ike nke mgbasa ha ọnụego na àgwà.
3. Usoro mgbasa nke HPMC capsules
A na-ekewa usoro mgbasa nke capsules HPMC n'ime usoro atọ:
Ogbo mmịnye mmiri nke mbụ: Mgbe nrichara ya, capsules HPMC na-ebu ụzọ amịpụta mmiri site na ihe ọṅụṅụ afọ. N'elu capsule na-aghọ mmiri wee malite nwayọọ nwayọọ. Ebe ọ bụ na ihe owuwu nke capsules HPMC nwere ụfọdụ ogo nnabata mmiri, ọkwa a na-adịkarị ngwa ngwa.
Ọzịza na mgbakasị ahụ: Mgbe ọ gbasasịrị mmiri, mgbidi capsule ahụ na-eji nwayọọ nwayọọ zaa ka ọ ghọọ oyi akwa gelatin. Ihe oyi akwa a na-eme ka capsule ahụ gbasaa ọzọ, na-ekpughe ihe dị n'ime ya wee hapụ ya. Oge a na-ekpebi ogo mgbasa nke capsule ma bụrụkwa isi ihe na mwepụta ọgwụ ma ọ bụ nri.
Oge mgbasa ozi zuru oke: Ka mgbasa ahụ na-aga n'ihu, capsule na-agbaze kpamkpam, a na-ewepụta ihe dị n'ime ya nke ọma, ahụ mmadụ nwere ike ịbanye ya. Na-emekarị n'ime nkeji 10 ruo 30, HPMC capsules nwere ike mezue usoro site na nkwụsịtụ ruo nkwụsịtụ.
Oge nzipu: Nov-07-2024