Nnukwu viscosity, obere viscosity HPMC na-egosipụta thixotropy ọbụlagodi n'okpuru okpomọkụ gel.

Hydroxypropylmethylcellulose (HPMC) bụ ngwakọta nke ghọworo ihe eji eme ihe n'ọtụtụ ụlọ ọrụ n'ihi njirimara multifunctional ya. A na-ejikarị ya eme ihe dị ka ihe mgbakwunye nri, ihe na-esi ísì ụtọ na ihe ịchọ mma, na ọbụna ngwa ahụike n'ọtụtụ ọgwụ. Ngwongwo pụrụ iche nke HPMC bụ omume thixotropic ya, nke na-enye ya ohere ịgbanwe viscosity na akụrụngwa n'okpuru ọnọdụ ụfọdụ. Na mgbakwunye, ma elu viscosity na obere viscosity HPMC nwere ihe onwunwe a, na-egosipụta thixotropy ọbụna n'okpuru gel okpomọkụ.

Thixotropy na-eme na HPMC mgbe ngwọta na-aghọ shear-thinning mgbe a na-etinye nrụgide ma ọ bụ kpalie, na-eme ka mbelata nke viscosity. Omume a nwekwara ike gbanwee; mgbe e wepụrụ nrụgide ahụ ma hapụ ihe ngwọta ahụ ka ọ zuru ike, viscosity ji nwayọọ nwayọọ laghachi na ọnọdụ ya dị elu. Ihe onwunwe a pụrụ iche na-eme HPMC ka ọ bụrụ akụrụngwa bara uru n'ọtụtụ ụlọ ọrụ ka ọ na-enye ohere maka ngwa dị nro na nhazi dị mfe.

Dị ka nonionic hydrocolloid, HPMC zaa na mmiri na-etolite a gel. Ogo nke ọzịza na gelling na-adabere na ịdị arọ molekụla na ntinye nke polymer, pH na okpomọkụ nke ngwọta. Nnukwu viscosity HPMC na-enwekarị ibu molekụla dị elu ma na-emepụta gel viscosity dị elu, ebe HPMC viscosity dị ala nwere ịdị arọ molekụla dị ala ma na-emepụta gel dị obere. Otú ọ dị, n'agbanyeghị ọdịiche ndị a na arụmọrụ, ụdị abụọ nke HPMC na-egosipụta thixotropy n'ihi mgbanwe nhazi nke na-eme na ọkwa molecular.

Omume thixotropic nke HPMC bụ n'ihi nhazi nke ụdọ polymer n'ihi nrụgide siri ike. Mgbe a na-etinye nrụgide siri ike na HPMC, ụdọ polymer na-ejikọta na ntụziaka nke nrụgide etinyere, na-akpata mbibi nke usoro netwọk akụkụ atọ nke dị na enweghị nchekasị. Mmebi nke netwọk na-ebute mbelata nke viscosity ngwọta. Mgbe ewepụsịrị nrụgide ahụ, ụdọ polymer na-ahazigharị n'akụkụ nghazi mbụ ha, wughachi netwọkụ ahụ wee weghachi viscosity.

HPMC na-egosipụtakwa thixotropy n'okpuru okpomọkụ gelling. The jel okpomọkụ bụ okpomọkụ nke polymer chains cross-njikọ na-etolite a atọ akụkụ netwọk, akpụ a gel. Ọ dabere na ntinye uche, ịdị arọ molekụla na pH nke ngwọta nke polymer. Gel na-esi na ya pụta nwere nnukwu viscosity na ọ dịghị agbanwe ngwa ngwa n'okpuru nrụgide. Agbanyeghị, n'okpuru okpomọkụ gelation, ihe ngwọta HPMC nọgidere na-abụ mmiri mmiri, mana ọ ka gosipụtara omume thixotropic n'ihi ọnụnọ nke usoro netwọkụ nke emebere nke ọma. Netwọk nke akụkụ ndị a mebere na-akụda n'okpuru nrụgide, na-ebute mbelata nke viscosity. Omume a bara uru n'ọtụtụ ngwa ebe ngwọta dị mkpa ka ọ na-asọ ngwa ngwa mgbe a kpalitere.

HPMC bụ kemịkalụ nwere ọtụtụ ihe pụrụ iche, otu n'ime ha bụ omume thixotropic ya. Ma elu viscosity na obere viscosity HPMC nwere ihe onwunwe a, na-egosipụta thixotropy ọbụna n'okpuru gel okpomọkụ. Njirimara a na-eme ka HPMC bụrụ ihe bara uru n'ọtụtụ ụlọ ọrụ na-achọ ngwọta na-edozi ọsọ dị mfe iji hụ na ngwa dị nro. N'agbanyeghị ọdịiche dị na ihe onwunwe dị n'etiti nnukwu viscosity na obere viscosity HPMC, omume thixotropic ha na-eme n'ihi nhazi na nkwụsịtụ nke nhazi netwọk nke akụkụ kpụrụ. N'ihi ihe ndị pụrụ iche ya, ndị na-eme nchọpụta na-enyocha ngwa dị iche iche nke HPMC mgbe niile, na-atụ anya ịmepụta ngwaahịa ọhụrụ na inye ngwọta dị mma maka ndị na-azụ ahịa gburugburu ụwa.


Oge nzipu: Ọgọst-23-2023