Hydroxypropyl methylcellulose (HPMC) na hypromellose bụ n'ezie otu ngwakọta, na a na-ejikarị okwu ndị ahụ eme ihe n'otu n'otu. Ndị a bụ aha mgbagwoju anya maka ụdị polymers nke dabeere na cellulose nke nwere ọtụtụ ngwa na ụlọ ọrụ dị iche iche gụnyere ọgwụ, nri na ihe ịchọ mma.
1.Chemical Ọdịdị na mejupụtara:
Hydroxypropylmethylcellulose (HPMC) bụ mgbanwe sịntetik nke cellulose, polymer eke dị na mgbidi cell osisi. A na-enweta usoro kemịkalụ nke HPMC site na iwebata hydroxypropyl na otu methyl na ndabere nke cellulose. Otu hydroxypropyl na-eme ka cellulose na-agbaze n'ime mmiri, na otu methyl na-eme ka nkwụsi ike ya dịkwuo elu ma na-ebelata mmeghachi omume ya.
2. Usoro mmepụta:
Mmepụta nke hydroxypropyl methylcellulose gụnyere iji propylene oxide na-agwọ cellulose iji webata otu hydroxypropyl wee jiri methyl chloride tinye otu methyl. Enwere ike ịhazi ogo nke nnọchi (DS) nke hydroxypropyl na methyl n'oge usoro nrụpụta, na-ebute akara ule dị iche iche nke HPMC nwere ihe dị iche iche.
3. Njirimara anụ ahụ:
HPMC bụ ntụ ntụ na-acha ọcha ruo ntakịrị na-acha ọcha, enweghị isi na enweghị ụtọ. Njirimara anụ ahụ ya, dị ka viscosity na solubility, na-adabere n'ókè nke nnọchi na ịdị arọ molekụla nke polymer. N'okpuru ọnọdụ nkịtị, ọ na-adị mfe soluble na mmiri, na-emepụta ngwọta na-enweghị atụ na enweghị agba.
4. Ebumnuche ahụike:
Otu n'ime ngwa ngwa nke HPMC dị na ụlọ ọrụ ọgwụ. A na-eji ya eme ihe n'ọtụtụ ebe dị ka ihe na-emepụta ọgwụ ma na-arụ ọrụ dị iche iche na nkwadebe ọgwụ. A na-ahụkarị HPMC n'ụdị usoro onunu siri ike dịka mbadamba, capsules, na ọgwụ. Ọ na-eme dị ka ihe nkedo, na-ekesa, na onye ntọhapụ a na-achịkwa, na-enye aka na nkwụsi ike zuru oke na bioavailability nke ọgwụ.
5. Ọrụ na nkwadebe ntọhapụ a na-achịkwa:
Ikike nke HPMC ịmepụta gels na ngwọta mmiri na-eme ka ọ baa uru na nhazi ọgwụ na-achịkwa. Site n'ịgbanwe viscosity na ihe na-emepụta gel, ndị ọkà mmụta sayensị na-ahụ maka ọgwụ nwere ike ịchịkwa ọnụego ntọhapụ nke ihe ndị na-arụ ọrụ, si otú a na-enweta ọgwụ na-adịgide adịgide na ogologo oge.
6. Ngwa na ụlọ ọrụ nri:
N'ụlọ ọrụ nri, a na-eji HPMC eme ihe dị ka thickener, stabilizer na emulsifier. Ọ na-eme ka ụdị nri dị iche iche dịkwuo mma, gụnyere sauces, ofe na ngwaahịa mmiri ara ehi. Na mgbakwunye, a na-eji HPMC eme achịcha na-enweghị gluten iji kwalite nhazi na ihe na-eme ka ahụ dị nro nke ngwaahịa na-enweghị gluten.
7. Ihe owuwu na ihe eji ewu ụlọ:
A na-eji HPMC eme ihe n'ụlọ ọrụ ihe owuwu na ngwaahịa ndị dị ka nrapado tile, plasta dabeere na ciment na ihe ndị dabeere na gypsum. Ọ na-eme ka usoro nhazi ahụ dịkwuo mma, njigide mmiri na ihe nrapado nke ngwaahịa ndị a.
8. Ihe ịchọ mma na ngwaahịa nlekọta onwe onye:
Hypromellose bụkwa ihe a na-ahụkarị na ihe ịchọ mma na ngwaahịa nlekọta onwe onye. A na-eji ya na ude, lotions na shampoos n'ihi na ọ na-eme ka ọ sie ike ma na-eme ka ọ dị ike. Na mgbakwunye, ọ na-enyere aka melite nhazi na mmetụta nke ngwaahịa ahụ n'ozuzu ya.
9. Ihe mkpuchi ihe nkiri na ọgwụ:
A na-ejikarị HPMC eme ihe na ụlọ ọrụ ọgwụ maka mkpuchi ihe nkiri nke mbadamba. Mbadamba ụrọ nke ihe nkiri na-enye ọdịdị dị mma, nkpuchi uto na nchebe megide ihe ndị metụtara gburugburu ebe obibi. Ihe nkiri HPMC na-enye mkpuchi dị nro na nke edo, na-eme ka ogo ngwaahịa ọgwụ ahụ dịkwuo mma.
13. Nkwubi okwu:
Hydroxypropyl methylcellulose (HPMC) na hypromellose na-ezo aka na otu polymer nke nwere cellulose nke nwere ngwa dị iche iche na ọgwụ, nri, ihe ịchọ mma, na ihe owuwu. Njirimara ya pụrụ iche, dị ka solubility, nkwụsi ike na biodegradability, na-enye aka n'iji ya eme ihe. The versatility nke HPMC dị iche iche ụlọ ọrụ pụta ìhè mkpa ya dị ka a multifunctional ihe, na aka iso re.ọchụchọ na mmepe nwere ike ikpughe ngwa ọzọ n'ọdịnihu.
Nlebanya zuru oke a chọrọ inye nkọwa zuru ezu nke hydroxypropyl methylcellulose na hypromellose, kọwapụta mkpa ha dị n'akụkụ dị iche iche, ma kọwaa ọrụ ha n'ịkpụzi ọtụtụ ngwaahịa na usoro.
Oge nzipu: Dec-21-2023